SCHEMBL1635618

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1636724	0.95	AKR1B1 (0.39)	AKR1B1MCL1MAOBCA12CA9
	SCHEMBL29828999	0.86	ALOX5 (0.46)	MCL1MAOBCA12CA9GPR35
	SCHEMBL21412957	0.86	ALOX5 (0.46)	MCL1MAOBCA12CA9GPR35
	SCHEMBL9889836	0.84	CYP1A1 (0.38)	AKR1B1MCL1MAOBCA12CA9
	SCHEMBL22889690	0.83	HSD17B1 (0.41)	AKR1B1MCL1MAOBCA12CA9
	SCHEMBL23098285	0.82	AHR (0.51)	MCL1KDM4EALDH1A1RAB9ACYP1A2
	SCHEMBL23230657	0.82	AHR (0.50)	KDM4EALDH1A1RAB9ACYP1A2MEN1
	SCHEMBL1635989	0.82	GPR35 (0.37)	AKR1B1MCL1CA12CA9GPR35
	SCHEMBL16806196	0.82	MAPKAPK2 (0.38)	CA9NUDT1KDM4ERAB9APTPN1
	SCHEMBL12811216	0.82	ALDH1A1 (0.33)	KDM4EALDH1A1CYP1A2PIK3CDPIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.