SCHEMBL16358274

SCHEMBL16358274

CCCCOSc1ccc2c(c1)c1cc(CCCC)ccc1n2-c1ccc(N(c2ccccc2)c2ccc(/C=C/c3ccccc3)cc2)cc1

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RORA P35398 1/20 0.32
RORC P51449 1/20 0.32
RORB Q92753 1/20 0.32
PPARG P37231 1/20 0.31
PPARA Q07869 1/20 0.31
PLA2G4A P47712 1/20 0.30
CHRNA7 P36544 1/20 0.30
CHRNA10 Q9GZZ6 1/20 0.30
CHRNA9 Q9UGM1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10123768 0.88 RORA (0.38) RORARORCRORBPLA2G4A
SCHEMBL10123840 0.87 RORA (0.39) RORARORCRORBPLA2G4A
SCHEMBL10123637 0.84 PLA2G4A (0.38) RORARORCRORBPLA2G4A
SCHEMBL10123708 0.83 PLA2G4A (0.38) RORARORCRORBPLA2G4A
SCHEMBL16358943 0.78 KDM4E (0.40)
SCHEMBL10123765 0.78 RELA (0.39) RORARORCRORBPPARGPLA2G4A
SCHEMBL13932489 0.78 RORA (0.44) RORARORCRORBPLA2G4A
SCHEMBL10123645 0.77 KDM4E (0.38) RORARORCRORBPLA2G4A
SCHEMBL13620181 0.77 HSD11B1 (0.42) RORARORCRORBPLA2G4A
SCHEMBL10123836 0.76 APP (0.38) RORARORCRORBPPARGPLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007043371-A1 STILBENE DERIVATIVES, LIGHT-EMITTING ELEMENT AND LIGHT-EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-04-19 WO disclosed