Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 6/20 | 0.53 |
| ▸ | HTR1B | P28222 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16358589 | 0.76 | APLNR (0.33) | APLNR | |
| SCHEMBL915191 | 0.70 | POLB (0.43) | HTR1DHTR1BALDH1A1POLBMEN1 | |
| SCHEMBL849673 | 0.70 | GRM5 (0.37) | APLNR | |
| SCHEMBL21192359 | 0.69 | HTR1D (0.57) | HTR1DHTR1BALDH1A1POLBMEN1 | |
| SCHEMBL2989162 | 0.69 | HTR1D (0.56) | HTR1DHTR1BALDH1A1POLBMEN1 | |
| SCHEMBL9047891 | 0.68 | HTR1D (0.61) | HTR1DHTR1BALDH1A1POLBMEN1 | |
| SCHEMBL28784149 | 0.67 | RXRA (0.42) | HTR1DALDH1A1POLBTSHR | |
| SCHEMBL28285675 | 0.67 | ALDH1A1 (0.51) | HTR1DHTR1BALDH1A1POLBMEN1 | |
| SCHEMBL11221925 | 0.65 | HTR1D (0.56) | HTR1DHTR1BALDH1A1POLBMEN1 | |
| SCHEMBL11441560 | 0.65 | HTR1D (0.56) | HTR1DHTR1BALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010126030-A1 | SPIROIMIDAZOLONE DERIVATIVE | 中外製薬株式会社 (JP) | 2010-11-04 | — | — | WO | disclosed |