Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 7/20 | 0.56 |
| ▸ | HTR1B | P28222 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL893283 | 0.76 | ALDH1A1 (0.41) | HTR1DTSHRTP53CYP3A4TDP1 | |
| SCHEMBL531025 | 0.76 | RAPGEF4 (0.46) | HTR1DHTR1BTSHRLMNAMAPK1 | |
| SCHEMBL14959898 | 0.75 | HTR1D (0.56) | HTR1DHTR1BPOLBTSHRHTR1A | |
| SCHEMBL11223055 | 0.75 | HTR1D (0.68) | HTR1DHTR1BPOLBTSHRHTR1A | |
| SCHEMBL11441560 | 0.75 | HTR1D (0.56) | HTR1DHTR1BPOLBTSHRHTR1A | |
| SCHEMBL11221925 | 0.75 | HTR1D (0.56) | HTR1DHTR1BPOLBTSHRHTR1A | |
| SCHEMBL21472699 | 0.74 | RAPGEF4 (0.40) | TSHRCHRM1ADRA1AHTR2BCYP3A4 | |
| SCHEMBL20669667 | 0.72 | PTGS2 (0.34) | TP53HTR2AHTR2CHTR2B | |
| SCHEMBL17393753 | 0.72 | GABRA1 (0.40) | HTR1DHTR1BPOLBTSHRMAPT | |
| SCHEMBL9250482 | 0.72 | GABRA1 (0.46) | HTR1DHTR1BPOLBTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103351343-A | Synthetic method for xylometazoline hydrochloride | TIANJIN HUAJIN PHARMACEUTICAL CO LTD | 2013-10-16 | — | — | CN | claimed |
| CN-117074566-A | Method for detecting genotoxic impurities in oxymetazoline hydrochloride | 常州亚邦制药有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-103351343-A | Synthetic method for xylometazoline hydrochloride | TIANJIN HUAJIN PHARMACEUTICAL CO LTD | 2013-10-16 | — | — | CN | disclosed |
| US-7781470-B2 | Aminodicarboxylic acid derivatives having pharmaceutical properties | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-08-24 | — | — | US | disclosed |
| US-20090203906-A1 | NOVEL AMINODICARBOXYLIC ACID DERIVATIVES HAVING PHARMACEUTICAL PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 2009-08-13 | — | — | US | disclosed |
| US-7087644-B1 | Derivatives of dicarboxylic acid having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2006-08-08 | — | — | US | disclosed |
| US-20060094769-A1 | Novel aminodicarboxylic acid derivatives having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203906-A1 | NOVEL AMINODICARBOXYLIC ACID DERIVATIVES HAVING PHARMACEUTICAL PROPERTIES | DDC, AADAT, PTGIS | HTR1D 2466/4885HTR1B 1008/4885POLB 4758/4885 |
| US-20060094769-A1 | Novel aminodicarboxylic acid derivatives having pharmaceutical properties | DDC, AADAT, PTGIS | HTR1D 2466/4885HTR1B 1008/4885POLB 4758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.