Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | VNN1 | O95497 | 6/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18097664 | 0.77 | SRD5A2 (0.56) | ALDH1A1HTTROCK2ROCK1VNN1 | |
| SCHEMBL27780305 | 0.74 | NOTUM (0.35) | NOTUMVNN1NPC1RAB9ASRD5A2 | |
| SCHEMBL27535758 | 0.74 | ALDH1A1 (0.53) | ALDH1A1HTTROCK2ROCK1MAP4K4 | |
| Hydrochloric Acid SCHEMBL27846469 | 0.72 | ALDH1A1 (0.51) | ALDH1A1HTTROCK2ROCK1MAP4K4 | |
| SCHEMBL8871249 | 0.70 | ROCK2 (0.44) | ALDH1A1HTTROCK2ROCK1VNN1 | |
| SCHEMBL4810366 | 0.68 | LMNA (0.53) | ALDH1A1HTTNPC1RAB9ASRD5A2 | |
| SCHEMBL434576 | 0.68 | ALDH1A1 (0.56) | ALDH1A1HTTROCK2NPC1RAB9A | |
| SCHEMBL1784996 | 0.67 | PBRM1 (0.59) | ALDH1A1HTTROCK2NPC1MAP4K4 | |
| SCHEMBL6183850 | 0.65 | ALDH1A1 (0.41) | ALDH1A1HTTROCK1MAP4K4 | |
| SCHEMBL8695752 | 0.64 | ALDH1A1 (0.45) | ALDH1A1HTTPROKR1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932211-B2 | 4-(4-trifluoromethyl-3-thiobenzoyl)pyrazoles and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2011-04-26 | — | — | US | claimed |
| EP-2137160-B1 | 4-(4-TRIFLUOROMETHYL-3-THIOBENZOYL)PYRAZOLES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2010-10-27 | — | — | EP | claimed |
| CN-101679284-A | 4-(4-trifluoromethyl-3-thiobenzoyl)pyrazoles, and use thereof as herbicides | BAYER CROPSCIENCE AG | 2010-03-24 | — | — | CN | claimed |
| EP-2137160-A1 | 4-(4-TRIFLUOROMETHYL-3-THIOBENZOYL)PYRAZOLES, AND USE THEREOF AS HERBICIDES | Bayer CropScience AG (DE) | 2009-12-30 | — | — | EP | claimed |
| US-20090069184-A1 | 4-(4-trifluoromethyl-3-thiobenzoyl)pyrazoles and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2009-03-12 | — | — | US | claimed |
| WO-2008125214-A1 | 4-(4-TRIFLUOROMETHYL-3-THIOBENZOYL)PYRAZOLES, AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2008-10-23 | — | — | WO | claimed |
| EP-1980556-A1 | 4-(4-trifluor methyl-3-thiobenzoyl) pyrazoles and their application as herbicides | Bayer CropScience AG (DE) | 2008-10-15 | — | — | EP | claimed |
| CN-108349883-B | Method for synthesizing 2-alkyl-4-trifluoromethyl-3-alkylsulfonylbenzoic acid | 拜耳作物科学股份公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-108349885-B | Method for producing 2-alkyl-4-trifluoromethyl-3-alkylsulfonylbenzoic acids by chemoselective thioether oxidation | 拜耳作物科学股份公司 | 2020-05-15 | — | — | CN | disclosed |
| US-10435352-B2 | Method for synthesizing 2-alkyl-4-trifluoromethyl-3-alkylsulfonylbenzoic acids | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-10-08 | — | — | US | disclosed |
| US-10252990-B2 | Process for the preparation of 2-alkyl-4-trifluoromethyl-3-alkylsulphonylbenzoic acids by chemoselective thioether oxidation | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-04-09 | — | — | US | disclosed |
| US-20180354898-A1 | Process for the preparation of 2-alkyl-4-trifluoromethyl-3-alkylsulphonylbenzoic acids by chemoselective thioether oxidation | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-12-13 | — | — | US | disclosed |
| US-20180305302-A1 | METHOD FOR SYNTHESIZING 2-ALKYL-4-TRIFLUOROMETHYL-3-ALKYLSULFONYLBENZOIC ACIDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-10-25 | — | — | US | disclosed |
| US-20090069184-A1 | 4-(4-trifluoromethyl-3-thiobenzoyl)pyrazoles and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2009-03-12 | — | — | US | disclosed |
| WO-2008125214-A1 | 4-(4-TRIFLUOROMETHYL-3-THIOBENZOYL)PYRAZOLES, AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2008-10-23 | — | — | WO | disclosed |
| WO-2008125214-A1 | 4-(4-TRIFLUOROMETHYL-3-THIOBENZOYL)PYRAZOLES, AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2008-10-23 | — | — | WO | disclosed |
| WO-2008125214-A1 | 4-(4-TRIFLUOROMETHYL-3-THIOBENZOYL)PYRAZOLES, AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2008-10-23 | — | — | WO | disclosed |
| EP-1980556-A1 | 4-(4-trifluor methyl-3-thiobenzoyl) pyrazoles and their application as herbicides | Bayer CropScience AG (DE) | 2008-10-15 | — | — | EP | disclosed |
| EP-1980556-A1 | 4-(4-trifluor methyl-3-thiobenzoyl) pyrazoles and their application as herbicides | Bayer CropScience AG (DE) | 2008-10-15 | — | — | EP | disclosed |
| EP-1980556-A1 | 4-(4-trifluor methyl-3-thiobenzoyl) pyrazoles and their application as herbicides | Bayer CropScience AG (DE) | 2008-10-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180305302-A1 | METHOD FOR SYNTHESIZING 2-ALKYL-4-TRIFLUOROMETHYL-3-ALKYLSULFONYLBENZOIC ACIDS | ARSA, ABL1, CYP2B6 | ALDH1A1 617/4885HTT 2633/4885PROKR1 4849/4885 |
| US-20180354898-A1 | Process for the preparation of 2-alkyl-4-trifluoromethyl-3-alkylsulphonylbenzoic acids by chemoselective thioether oxidation | TST, CYP2F1, SULT1A1 | ALDH1A1 215/4885HTT 3486/4885PROKR1 4833/4885 |
| US-20090069184-A1 | 4-(4-trifluoromethyl-3-thiobenzoyl)pyrazoles and their use as herbicides | TH, DDT, CYP4X1 | ALDH1A1 680/4885HTT 592/4885PROKR1 4127/4885 |
| US-10435352-B2 | Method for synthesizing 2-alkyl-4-trifluoromethyl-3-alkylsulfonylbenzoic acids | ARSA, ABL1, CYP2B6 | ALDH1A1 617/4885HTT 2633/4885PROKR1 4849/4885 |
| US-10252990-B2 | Process for the preparation of 2-alkyl-4-trifluoromethyl-3-alkylsulphonylbenzoic acids by chemoselective thioether oxidation | TST, CYP2F1, SULT1A1 | ALDH1A1 215/4885HTT 3486/4885PROKR1 4833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.