SCHEMBL1636145

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5028208	0.97	KDM4E (0.47)	KDM4EATML3MBTL1ALOX5PRKDC
	SCHEMBL16390630	0.93	KDM4E (0.41)	KDM4EATML3MBTL1ALOX5PRKDC
	SCHEMBL17228757	0.90	KDM4E (0.41)	KDM4EATML3MBTL1ALOX5PRKDC
	SCHEMBL14733734	0.90	KDM4E (0.41)	KDM4EATML3MBTL1ALOX5PRKDC
	SCHEMBL21709118	0.90	KDM4E (0.41)	KDM4EATML3MBTL1ALOX5PRKDC
	SCHEMBL21583638	0.89	ALOX5 (0.52)	KDM4EATML3MBTL1ALOX5PRKDC
	SCHEMBL21583636	0.89	ALOX5 (0.52)	KDM4EATML3MBTL1ALOX5PRKDC
	SCHEMBL17837004	0.89	KDM4E (0.40)	KDM4EATML3MBTL1ALOX5PRKDC
	SCHEMBL17871071	0.89	ALOX5 (0.55)	KDM4EATML3MBTL1ALOX5PRKDC
	SCHEMBL1635446	0.89	ALOX5 (0.45)	KDM4EATML3MBTL1ALOX5PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.