SCHEMBL1636389

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1636331	0.88	ALDH1A1 (0.42)	ALOX5HPGDALDH1A1TSHRMAPK1
	SCHEMBL1637805	0.84	PRKDC (0.43)	ALOX5HPGDALDH1A1TSHRHSD17B10
	SCHEMBL430447	0.84	ALDH1A1 (0.55)	ALOX5HPGDALDH1A1TSHRMAPK1
	SCHEMBL1635701	0.82	ALDH1A1 (0.48)	ALOX5HPGDALDH1A1TSHRMAPK1
	SCHEMBL1636396	0.81	ALOX5 (0.44)	ALOX5ALDH1A1TSHRHSD17B10HIF1A
	SCHEMBL4549400	0.81	CYP11B1 (0.46)	ALOX5HPGDALDH1A1TSHRMAPK1
	SCHEMBL24217268	0.81	ALDH1A1 (0.42)	HPGDALDH1A1TSHRMAPK1HSD17B10
	SCHEMBL1636391	0.81	PRKDC (0.46)	ALOX5ALDH1A1HSD17B10MEN1KMT2A
	SCHEMBL1636326	0.81	ALOX5 (0.44)	ALOX5ALDH1A1TSHRHSD17B10HIF1A
	SCHEMBL4549402	0.80	CYP11B1 (0.45)	ALOX5HPGDALDH1A1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.