Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1S | P09871 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20114490 | 0.78 | PARP1 (0.48) | PARP1SMN1; SMN2CTSL | |
| SCHEMBL20350852 | 0.77 | ALDH1A1 (0.38) | SMN1; SMN2GAANFKB1 | |
| SCHEMBL21339902 | 0.76 | OGG1 (0.52) | SMN1; SMN2IDO1CTSLGAA | |
| SCHEMBL441773 | 0.76 | NOS1 (0.40) | PARP1SMN1; SMN2IDO1HPGDL3MBTL1 | |
| SCHEMBL2945465 | 0.76 | NOS1 (0.40) | PARP1SMN1; SMN2IDO1HPGDL3MBTL1 | |
| SCHEMBL16543881 | 0.75 | C1S (0.59) | C1SPARP1SMN1; SMN2CTSLGAA | |
| SCHEMBL3725357 | 0.73 | NPC1 (0.53) | C1SPARP1SMN1; SMN2L3MBTL1 | |
| SCHEMBL401199 | 0.73 | L3MBTL1 (0.64) | PARP1SMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL6961313 | 0.73 | C1S (0.62) | C1SPARP1SMN1; SMN2IDO1CTSL | |
| SCHEMBL28127816 | 0.73 | NPC1 (0.53) | C1SPARP1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2236500-B1 | BICYCLO-SUBSTITUTED PYRAZOLON AZO DERIVATIVES, PREPARATION PROCESS AND PHARMACEUTICAL USE THEREOF | JIANGSU HENGRUI MEDICINE CO (CN) | 2014-12-24 | — | — | EP | disclosed |