SCHEMBL1637551

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1637298	1.00	CYP1A1 (0.45)	CYP1A1CYP1B1ESR1ESR2ALOX5
	SCHEMBL1637399	0.98	ESR1 (0.47)	CYP1A1CYP1B1ESR1ESR2ALOX5
	SCHEMBL1636430	0.98	CYP1A1 (0.44)	CYP1A1CYP1B1ESR1ESR2ALOX5
	SCHEMBL1637303	0.95	HSD17B1 (0.46)	CYP1A1CYP1B1ESR1ESR2ALOX5
	SCHEMBL25050917	0.92	CYP1A1 (0.43)	CYP1A1CYP1B1ESR1ESR2ALOX5
	SCHEMBL9889876	0.90	CYP1A1 (0.41)	CYP1A1CYP1B1ESR1ESR2ALOX5
	SCHEMBL1637009	0.90	ALOX5 (0.44)	CYP1A1CYP1B1ALOX5CYP1A2CYP2C9
	SCHEMBL25052872	0.89	CYP1A1 (0.42)	CYP1A1CYP1B1ESR1ESR2ALOX5
	SCHEMBL10122442	0.89	CYP1A1 (0.42)	CYP1A1CYP1B1ESR1ESR2ALOX5
	SCHEMBL20127636	0.89	CYP1A1 (0.42)	CYP1A1CYP1B1ESR1ESR2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.