SCHEMBL1638457

SCHEMBL1638457

C=COC(CCC)c1ccccc1C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.40
KDM4E B2RXH2 3/20 0.40
MEN1 O00255 1/20 0.40
RECQL P46063 1/20 0.40
ALDH1A1 P00352 6/20 0.40
SLC37A4 O43826 1/20 0.38
TDP1 Q9NUW8 2/20 0.38
GAA P10253 1/20 0.38
KDM4C Q9H3R0 1/20 0.37
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 2/20 0.36
HPGD P15428 1/20 0.36
HTT P42858 1/20 0.36
TSHR P16473 1/20 0.35
POLB P06746 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
TP53 P04637 1/20 0.35
CA12 O43570 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29017557 0.82 SLC37A4 (0.49) KMT2AKDM4EMEN1RECQLALDH1A1
SCHEMBL2593871 0.81 TAS1R3 (0.36) KMT2AKDM4EMEN1RECQLALDH1A1
SCHEMBL4371723 0.79 ALDH1A1 (0.41) KMT2AKDM4EMEN1RECQLALDH1A1
SCHEMBL28948581 0.79 SLC37A4 (0.35) SLC37A4KDM4C
SCHEMBL2509479 0.79 SLC37A4 (0.35) SLC37A4KDM4C
SCHEMBL25359529 0.77
SCHEMBL25361269 0.76 IDO1 (0.42) KMT2AMEN1ALDH1A1LMNA
SCHEMBL25361745 0.76 CASP1 (0.38) KMT2AMEN1ALDH1A1GAAHTT
SCHEMBL9840091 0.75 ALDH1A1 (0.44) KMT2AKDM4EMEN1RECQLALDH1A1
SCHEMBL25385930 0.75 AOC3 (0.39) KMT2AMEN1ALOX15TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8770304-B2 Open-hole wellbore lining SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2014-07-08 US disclosed
US-8602114-B2 Open-hole wellbore lining SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2013-12-10 US disclosed
US-20110183873-A1 Open-Hole Wellbore Lining SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2011-07-28 US disclosed
US-20110162854-A1 OPEN-HOLE WELLBORE LINING SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2011-07-07 US disclosed
US-7931091-B2 Open-hole wellbore lining SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2011-04-26 US disclosed
EP-2197973-A1 OPEN-HOLE WELLBORE LINING Schlumberger Technology B.V. (NL) 2010-06-23 EP disclosed
WO-2009044137-A1 OPEN-HOLE WELLBORE LINING SCHLUMBERGER TECHNOLOGY B.V. (NL) 2009-04-09 WO disclosed
US-20090090514-A1 OPEN-HOLE WELLBORE LINING SCHLUMBERGER TECHNOLOGY CORPORATION 2009-04-09 US disclosed