Sugi Predict

Sugi Predict / Compounds / SCHEMBL16388451

SCHEMBL16388451

SCHEMBL16388451

c1cc(-c2ccc3oc4ccc(-n5c6ccccc6n6c7ccccc7nc56)cc4c3c2)cc(-c2ccc3oc4ccc(-n5c6ccccc6n6c7ccccc7nc56)cc4c3c2)c1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.33
▸ HPGD P15428 3/20 0.33
▸ KDM4E B2RXH2 2/20 0.33
▸ PLA2G2A P14555 2/20 0.33
▸ PLA2G4A P47712 2/20 0.33
▸ PLA2G10 O15496 1/20 0.33
▸ ESR1 P03372 1/20 0.32
▸ ESR2 Q92731 1/20 0.32
▸ PRKDC P78527 1/20 0.32
▸ GAA P10253 2/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.32
▸ CHEK2 O96017 1/20 0.31
▸ ADORA2B P29275 2/20 0.31
▸ ADORA1 P30542 2/20 0.31
▸ SMN1; SMN2 Q16637 2/20 0.30
▸ NPC1 O15118 1/20 0.30
▸ LMNA P02545 1/20 0.30
▸ TP53 P04637 1/20 0.30
▸ MAPT P10636 1/20 0.30
▸ PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12800973 0.97 ADORA2B (0.33) ALDH1A1HPGDKDM4EPLA2G2APLA2G4A
SCHEMBL12800969 0.96 CHEK2 (0.33) ALDH1A1HPGDKDM4EPLA2G2APLA2G4A
SCHEMBL14952491 0.95 ALDH1A1 (0.33) ALDH1A1HPGDKDM4EPLA2G2APLA2G4A
SCHEMBL12801026 0.94 CHEK2 (0.31) ALDH1A1HPGDKDM4ECHEK2SMN1; SMN2
SCHEMBL15631676 0.94 ALDH1A1 (0.34) ALDH1A1HPGDKDM4EPLA2G2APLA2G4A
SCHEMBL12800972 0.92 KDM4E (0.33) ALDH1A1HPGDKDM4EPLA2G2APLA2G4A
SCHEMBL17993513 0.92 TP53 (0.38) HPGDKDM4EADORA1SMN1; SMN2NPC1
SCHEMBL12800974 0.92 KDM4E (0.33) ALDH1A1HPGDKDM4EPLA2G2APLA2G4A
SCHEMBL20408541 0.92 ALDH1A1 (0.34) ALDH1A1HPGDKDM4EPLA2G2APLA2G4A
SCHEMBL12800967 0.92 CHEK2 (0.33) ALDH1A1HPGDKDM4EL3MBTL1CHEK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3126371-B1 METAL COMPLEXES, COMPRISING CARBENE LIGANDS HAVING AN O-SUBSTITUTED NON-CYCLOMETALATED ARYL GROUP AND THEIR USE IN ORGANIC LIGHT EMITTING DIODES UDC IRELAND LTD (IE) 2021-11-10 — — EP disclosed
US-20200251667-A1 MONOSUBSTITUTED DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES FOR USE IN ORGANIC LIGHT EMITTING DIODES UDC IRELAND LTD (IE) 2020-08-06 — — US disclosed
EP-3608329-A1 MONOSUBSTITUTED DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES FOR USE IN ORGANIC LIGHT EMITTING DIODES UDC Ireland Limited (IE) 2020-02-12 — — EP disclosed
US-10431750-B2 4H-imidazo[1,2-a]imidazoles for electronic applications UDC IRELAND LIMITED (IE) 2019-10-01 — — US disclosed
EP-3266789-B1 MONOSUBSTITUTED DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES FOR USE IN ORGANIC LIGHT EMITTING DIODES UDC IRELAND LTD (IE) 2019-09-25 — — EP disclosed
US-20190273211-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications UDC IRELAND LTD (IE) 2019-09-05 — — US disclosed
US-10370396-B2 Metal complexes, comprising carbene ligands having an O-substituted non-cyclometallated aryl group and their use in organic light emitting diodes UDC IRELAND LIMITED (IE) 2019-08-06 — — US disclosed
US-10290817-B2 Luminescent diaza-monoaza-and benzimidazole metal carbene complexes for use in electronic devices such as OLEDs UDC IRELAND LIMITED (IE) 2019-05-14 — — US disclosed
US-20190016740-A1 Metal Complexes, Comprising Carbene Ligands Having an O-Substituted Non-Cyclometalated Aryl Group and Their Use in Organic Light Emitting Diodes UDC IRELAND LTD (IE) 2019-01-17 — — US disclosed
US-20180127448-A1 Metal Complexes, Comprising Carbene Ligands Having an O-Substituted Non-Cyclometalated Aryl Group and Their Use in Organic Light Emitting Diodes UDC IRELAND LTD (IE) 2018-05-10 — — US disclosed
US-20160190480-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications BASF SE (DE) 2016-06-30 — — US disclosed
US-20160190480-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications BASF SE (DE) 2016-06-30 — — US disclosed
EP-3034508-A1 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2016-06-22 — — EP disclosed
US-20160172606-A1 LUMINESCENT DIAZA-MONOAZA-AND BENZIMIDAZOLE METAL CARBENE COMPLEXES FOR USE IN ELECTRONIC DEVICES SUCH AS OLEDS BASF SE (DE) 2016-06-16 — — US disclosed
US-20160172606-A1 LUMINESCENT DIAZA-MONOAZA-AND BENZIMIDAZOLE METAL CARBENE COMPLEXES FOR USE IN ELECTRONIC DEVICES SUCH AS OLEDS BASF SE (DE) 2016-06-16 — — US disclosed
EP-2688889-B1 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2016-05-18 — — EP disclosed
WO-2015150203-A1 METAL COMPLEXES, COMPRISING CARBENE LIGANDS HAVING AN O-SUBSTITUTED NON-CYCLOMETALATED ARYL GROUP AND THEIR USE IN ORGANIC LIGHT EMITTING DIODES BASF SE (DE) 2015-10-08 — — WO disclosed
WO-2015014944-A1 LUMINESCENT DIAZA- MONOAZA- AND BENZIMIDAZOLE METAL CARBENE COMPLEXES FOR USE IN ELECTRONIC DEVICES SUCH AS OLEDS BASF SE (DE) 2015-02-05 — — WO disclosed
WO-2015014835-A1 LUMINESCENT DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES BASF SE (DE) 2015-02-05 — — WO disclosed
WO-2015000955-A1 MONOSUBSTITUTED DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES FOR USE IN ORGANIC LIGHT EMITTING DIODES BASF SE (DE) 2015-01-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160172606-A1 LUMINESCENT DIAZA-MONOAZA-AND BENZIMIDAZOLE METAL CARBENE COMPLEXES FOR USE IN ELECTRONIC DEVICES SUCH AS OLEDS OCIAD1, OCIAD2, OXA1L ALDH1A1 857/4885HPGD 1475/4885KDM4E 2664/4885
US-10431750-B2 4H-imidazo[1,2-a]imidazoles for electronic applications EIF4A1, ITPR2, ITPR1 ALDH1A1 355/4885HPGD 1129/4885KDM4E 1166/4885
US-20190273211-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications PAH, NISCH, KCNH1 ALDH1A1 405/4885HPGD 486/4885KDM4E 1128/4885
US-20190016740-A1 Metal Complexes, Comprising Carbene Ligands Having an O-Substituted Non-Cyclometalated Aryl Group and Their Use in Organic Light Emitting Diodes ICOSLG, CD40LG, OCIAD1 ALDH1A1 1385/4885HPGD 1110/4885KDM4E 3918/4885
US-20200251667-A1 MONOSUBSTITUTED DIAZABENZIMIDAZOLE CARBENE METAL COMPLEXES FOR USE IN ORGANIC LIGHT EMITTING DIODES DDT, OCIAD1, OCIAD2 ALDH1A1 563/4885HPGD 761/4885KDM4E 2365/4885
US-10290817-B2 Luminescent diaza-monoaza-and benzimidazole metal carbene complexes for use in electronic devices such as OLEDs OCIAD1, OCIAD2, OXA1L ALDH1A1 857/4885HPGD 1475/4885KDM4E 2664/4885
US-10370396-B2 Metal complexes, comprising carbene ligands having an O-substituted non-cyclometallated aryl group and their use in organic light emitting diodes ICOSLG, CD40LG, OCIAD1 ALDH1A1 1475/4885HPGD 1052/4885KDM4E 3913/4885
US-20180127448-A1 Metal Complexes, Comprising Carbene Ligands Having an O-Substituted Non-Cyclometalated Aryl Group and Their Use in Organic Light Emitting Diodes ICOSLG, CD40LG, OCIAD1 ALDH1A1 1385/4885HPGD 1110/4885KDM4E 3918/4885
US-20160190480-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications PAH, NISCH, KCNH1 ALDH1A1 405/4885HPGD 486/4885KDM4E 1128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.