Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.49 |
| ▸ | MMP12 | P39900 | 4/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | BCKDK | O14874 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16395999 | 0.83 | HPGD (0.54) | MMP12MMP13ALDH1A1SMN1; SMN2 | |
| SCHEMBL16396143 | 0.78 | MMP12 (0.47) | GPR35MMP12MMP13PTPN1ALDH1A1 | |
| SCHEMBL15619574 | 0.76 | MCL1 (0.71) | GPR35TBXAS1MCL1BCL2L1RXFP1 | |
| SCHEMBL2895958 | 0.73 | GPR35 (0.58) | GPR35TBXAS1MCL1BCL2L1RXFP1 | |
| SCHEMBL2895162 | 0.73 | BCKDK (0.67) | GPR35TBXAS1MCL1BCL2L1RXFP1 | |
| SCHEMBL12153769 | 0.73 | MCL1 (0.71) | GPR35TBXAS1MCL1BCL2L1RXFP1 | |
| SCHEMBL2896302 | 0.72 | CES2 (0.63) | GPR35TBXAS1MCL1BCL2L1RXFP1 | |
| SCHEMBL16396231 | 0.71 | HDAC1 (0.55) | GPR35TBXAS1BCL2L1 | |
| SCHEMBL3572338 | 0.71 | GPR35 (0.55) | GPR35TBXAS1MCL1BCL2L1RXFP1 | |
| SCHEMBL10952974 | 0.71 | TBXAS1 (0.60) | GPR35TBXAS1MCL1BCL2L1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10562912-B2 | Heterocyclic derivatives and use thereof | C&C RESEARCH LABORATORIES (KR) | 2020-02-18 | — | — | US | disclosed |
| EP-3004057-B1 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS STAT 3 INHIBITORS | C&C RES LAB (KR) | 2018-07-25 | — | — | EP | disclosed |
| US-20160108056-A1 | HETEROCYCLIC DERIVATIVES AND USE THEREOF | C&C RESEARCH LABORATORIES (KR) | 2016-04-21 | — | — | US | disclosed |
| EP-3004057-A1 | HETEROCYCLIC DERIVATIVES AND USE THEREOF | C&C Research Laboratories (KR) | 2016-04-13 | — | — | EP | disclosed |
| WO-2014196793-A1 | HETEROCYCLIC DERIVATIVES AND USE THEREOF | C&C RESEARCH LABORATORIES (KR) | 2014-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160108056-A1 | HETEROCYCLIC DERIVATIVES AND USE THEREOF | STAT3, JAK2, STAT5A | GPR35 2270/4885TBXAS1 288/4885MMP12 640/4885 |
| US-10562912-B2 | Heterocyclic derivatives and use thereof | STAT3, JAK2, STAT5A | GPR35 2270/4885TBXAS1 288/4885MMP12 640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.