Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 5/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16405458 | 0.84 | ALDH1A1 (0.57) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL51058 | 0.83 | CYP2D6 (0.67) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL21002165 | 0.83 | CYP2D6 (0.67) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL1229448 | 0.82 | ESR1 (0.71) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL5636034 | 0.82 | KLF10 (0.78) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL30124085 | 0.82 | KLF10 (0.78) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL9290335 | 0.80 | CYP2D6 (0.62) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL28591107 | 0.80 | CYP2D6 (0.62) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL10026837 | 0.79 | ESR1 (0.50) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL10874465 | 0.78 | CYP2C19 (0.67) | CYP2D6ALDH1A1HPGDALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108698389-B | Multilayer film and method of manufacture | 日本瑞翁株式会社 | 2020-04-28 | — | — | CN | disclosed |
| US-9795549-B2 | 1,2-alkane polyol-containing composition | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2017-10-24 | — | — | US | disclosed |
| US-20170209441-A1 | AMINOQUINOLINE DERIVATIVES AND USES THEREOF | UNIVERSITY OF DELHI (IN) | 2017-07-27 | — | — | US | disclosed |
| US-9567316-B2 | Aminoquinoline derivatives and uses thereof | THE MCLEAN HOSPITAL CORPORATION (US) | 2017-02-14 | — | — | US | disclosed |
| US-20160045414-A1 | 1,2-ALKANE POLYOL-CONTAINING COMPOSITION | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2016-02-18 | — | — | US | disclosed |
| EP-2985017-A1 | 1,2-ALKANE POLYOL-CONTAINING COMPOSITION | Osaka Organic Chemical Ind., Ltd. (JP) | 2016-02-17 | — | — | EP | disclosed |
| US-20150023930-A1 | AMINOQUINOLINE DERIVATIVES AND USES THEREOF | THE MCLEAN HOSPITAL CORPORATION (US) | 2015-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150023930-A1 | AMINOQUINOLINE DERIVATIVES AND USES THEREOF | LRRK2, NLN, AADAT | CYP2D6 1830/4885ALDH1A1 2094/4885HPGD 879/4885 |
| US-20170209441-A1 | AMINOQUINOLINE DERIVATIVES AND USES THEREOF | LRRK2, NLRP3, AADAT | CYP2D6 1351/4885ALDH1A1 1990/4885HPGD 1667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.