Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6659336 | 0.96 | THRB (0.56) | THRBTHRA | |
| SCHEMBL7513989 | 0.95 | THRB (0.55) | THRBTHRA | |
| SCHEMBL1641063 | 0.93 | THRB (0.58) | THRBTHRA | |
| SCHEMBL7060536 | 0.91 | THRB (0.47) | THRBTHRA | |
| SCHEMBL6657910 | 0.90 | THRB (0.58) | THRBTHRA | |
| SCHEMBL6660665 | 0.90 | THRB (0.61) | THRBTHRA | |
| SCHEMBL6657417 | 0.89 | THRA (0.54) | THRBTHRA | |
| SCHEMBL6659652 | 0.89 | THRB (0.57) | THRBTHRA | |
| SCHEMBL1642150 | 0.88 | THRB (0.63) | THRBTHRA | |
| SCHEMBL7059649 | 0.88 | THRB (0.48) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098303-A1 | Method of promoting nail growth using thyromimetic compounds | DOHERTY NIALL S | 2011-04-28 | — | — | US | claimed |
| EP-1157001-B1 | OXAMIC ACIDS AND DERIVATIVES AS THYROID RECEPTOR LIGANDS | PFIZER PROD INC (US) | 2004-08-04 | — | — | EP | claimed |
| WO-2004047827-A1 | METHOD FOR PROMOTING NAIL GROWTH USING THYROMIMETIC COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2004-06-10 | — | — | WO | claimed |
| US-20030114521-A1 | Oxamic acids and derivatives as thyroid receptor ligands | CHIANG YUAN-CHING PHOEBE (US) | 2003-06-19 | — | — | US | claimed |
| US-6545018-B2 | Treating obesity, hyperlipidemia, glaucoma, arrhythmia, skin disorders, thyroid disease, hypothyroidism, diabetes mellitus, atherosclerosis, hypertension, coronary heart disease, hypercholesteremia, depression and osteoporosis | PFIZER INC. | 2003-04-08 | — | — | US | claimed |
| US-20030007941-A1 | Method of treating hair loss using thyromimetic compounds | CORNELIUS PETER (US) | 2003-01-09 | — | — | US | claimed |
| EP-1262177-A2 | Medical use of thyromimetic compounds to treat hair loss and compositions | Pfizer Products Inc. (US) | 2002-12-04 | — | — | EP | claimed |
| US-20020049226-A1 | Oxamic acids and derivatives as thyroid receptor ligands | CHIANG YUAN-CHING PHOEBE (US) | 2002-04-25 | — | — | US | claimed |
| WO-2002032408-A2 | COMBINATIONS OF A THYROMIMETIC COMPOUND AND A STATIN | NOVARTIS AG (CH) | 2002-04-25 | — | — | WO | claimed |
| EP-1157001-A1 | OXAMIC ACIDS AND DERIVATIVES AS THYROID RECEPTOR LIGANDS | Pfizer Products Inc. (US) | 2001-11-28 | — | — | EP | claimed |
| WO-2000051971-A1 | OXAMIC ACIDS AND DERIVATIVES AS THYROID RECEPTOR LIGANDS | PFIZER PRODUCTS INC. (US) | 2000-09-08 | — | — | WO | claimed |
| US-20110098303-A1 | Method of promoting nail growth using thyromimetic compounds | DOHERTY NIALL S | 2011-04-28 | — | — | US | disclosed |
| EP-1419173-B1 | PEPTIDES THAT BIND TO ATHEROSCLEROTIC LESIONS | NOVARTIS AG (CH) | 2008-11-26 | — | — | EP | disclosed |
| US-20080125433-A1 | Method of treating hair loss using thyromimetic compounds | CORNELIUS PETER | 2008-05-29 | — | — | US | disclosed |
| US-20070264194-A1 | Peptides That Bind To Atherosclerotic Lesions | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-11-15 | — | — | US | disclosed |
| US-20020049226-A1 | Oxamic acids and derivatives as thyroid receptor ligands | CHIANG YUAN-CHING PHOEBE (US) | 2002-04-25 | — | — | US | disclosed |
| WO-2002032408-A2 | COMBINATIONS OF A THYROMIMETIC COMPOUND AND A STATIN | NOVARTIS AG (CH) | 2002-04-25 | — | — | WO | disclosed |
| US-6326398-B1 | Oxamic acids and derivatives as thyroid receptor ligands | PFIZER INC. | 2001-12-04 | — | — | US | disclosed |
| EP-1157001-A1 | OXAMIC ACIDS AND DERIVATIVES AS THYROID RECEPTOR LIGANDS | Pfizer Products Inc. (US) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000051971-A1 | OXAMIC ACIDS AND DERIVATIVES AS THYROID RECEPTOR LIGANDS | PFIZER PRODUCTS INC. (US) | 2000-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114521-A1 | Oxamic acids and derivatives as thyroid receptor ligands | OXER1, THRA, TSHR | THRB 4/4885THRA 2/4885 |
| US-20080125433-A1 | Method of treating hair loss using thyromimetic compounds | TRHDE, TPO, THRB | THRB 3/4885THRA 4/4885 |
| US-20070264194-A1 | Peptides That Bind To Atherosclerotic Lesions | FABP3, CCL2, VCAM1 | THRB 1460/4885THRA 2609/4885 |
| US-20030007941-A1 | Method of treating hair loss using thyromimetic compounds | TRHDE, TPO, THRB | THRB 3/4885THRA 4/4885 |
| US-20020049226-A1 | Oxamic acids and derivatives as thyroid receptor ligands | OXER1, THRA, OXGR1 | THRB 4/4885THRA 2/4885 |
| US-20110098303-A1 | Method of promoting nail growth using thyromimetic compounds | TPO, POLR1C, TYR | THRB 29/4885THRA 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.