SCHEMBL16410044

SCHEMBL16410044

c1ccc(-n2c3ccccc3c3cc(-c4ccc5c(c4)c4ccc6c(c4n5-c4ccccc4)-c4ccccc4C64c5ccccc5-c5ccccc54)ccc32)cc1

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KMT2A Q03164 1/20 0.32
DUSP3 P51452 1/20 0.31
PTGER4 P35408 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15840145 0.95 KDM4E (0.32) KDM4EATML3MBTL1
SCHEMBL17759428 0.93 KDM4E (0.39) KDM4EATML3MBTL1KMT2ADUSP3
SCHEMBL15840162 0.93 PDK2 (0.33) KDM4EATML3MBTL1KMT2A
SCHEMBL18562964 0.93 KDM4E (0.37) KDM4EATML3MBTL1DUSP3
SCHEMBL17379812 0.92 KDM4E (0.35) KDM4EATML3MBTL1PTGER4
SCHEMBL15840227 0.92 KDM4E (0.42) KDM4EATML3MBTL1DUSP3
SCHEMBL18858188 0.92 KDM4E (0.36) KDM4EATML3MBTL1
SCHEMBL20199565 0.91 KDM4E (0.41) KDM4EATML3MBTL1DUSP3
SCHEMBL17279378 0.91 PDK2 (0.33)
SCHEMBL19653460 0.91 KDM4E (0.37) KDM4EATML3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917903-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 US disclosed
US-11917903-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 US disclosed
US-20230320191-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-10-05 US disclosed
US-20230320191-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-10-05 US disclosed
US-20230271989-A1 METAL COMPLEXES UDC IRELAND LIMITED (IE) 2023-08-31 US disclosed
US-20230271989-A1 METAL COMPLEXES UDC IRELAND LIMITED (IE) 2023-08-31 US disclosed
US-11737352-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-08-22 US disclosed
US-11737352-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-08-22 US disclosed
US-11659763-B2 Metal complexes MERCK PATENT GMBH 2023-05-23 US disclosed
US-11659763-B2 Metal complexes MERCK PATENT GMBH 2023-05-23 US disclosed
US-20180026209-A1 Metal Complexes MERCK PATENT GMBH (DE) 2018-01-25 US disclosed
US-20180026209-A1 Metal Complexes MERCK PATENT GMBH (DE) 2018-01-25 US disclosed
EP-2935276-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-11-01 EP disclosed
US-20170077418-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2017-03-16 US disclosed
US-20170077418-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2017-03-16 US disclosed
WO-2016124304-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2016-08-11 WO disclosed
US-20150337197-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-11-26 US disclosed
US-20150337197-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-11-26 US disclosed
US-9193747-B2 Organic electroluminescent device UDC IRELAND LIMITED (IE) 2015-11-24 US disclosed
WO-2014194971-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-12-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170077418-A1 ORGANIC ELECTROLUMINESCENT DEVICE EPCAM, L1CAM, LAGE3 KDM4E 2425/4885ATM 2599/4885L3MBTL1 107/4885
US-20230320191-A1 METAL COMPLEXES IMMT, MCU, SOD1 KDM4E 4470/4885ATM 4048/4885L3MBTL1 3259/4885
US-20230271989-A1 METAL COMPLEXES AP3M1, AP1M1, AP2M1 KDM4E 3576/4885ATM 3098/4885L3MBTL1 2773/4885
US-11737352-B2 Materials for organic electroluminescent devices EPB41, EPB41L2, MCM4 KDM4E 852/4885ATM 3851/4885L3MBTL1 2392/4885
US-20180026209-A1 Metal Complexes AP3M1, AP2M1, SOD1 KDM4E 3864/4885ATM 3554/4885L3MBTL1 2863/4885
US-11659763-B2 Metal complexes IMMT, MCU, SOD1 KDM4E 4470/4885ATM 4048/4885L3MBTL1 3259/4885
US-11917903-B2 Metal complexes NCLN, BICRA, AP3M1 KDM4E 3870/4885ATM 3416/4885L3MBTL1 2532/4885
US-20150337197-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES OR10J3, EML4, L1CAM KDM4E 2176/4885ATM 3105/4885L3MBTL1 734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.