SCHEMBL16429474

SCHEMBL16429474

CC(C)Oc1ccc(-c2cc(CC(CCN)NCCCN)cc(CC(CCN)NCCCN)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRMT3 O60678 2/20 0.40
▸ CARM1 Q86X55 2/20 0.40
▸ PRMT6 Q96LA8 2/20 0.40
▸ PRMT1 Q99873 2/20 0.40
▸ PRMT8 Q9NR22 2/20 0.40
▸ MEN1 O00255 2/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ MITF O75030 1/20 0.34
▸ MCL1 Q07820 2/20 0.33
▸ SIGMAR1 Q99720 1/20 0.32
▸ FFAR4 Q5NUL3 1/20 0.32
▸ MAP4K4 O95819 1/20 0.32
▸ ERN1 O75460 1/20 0.32
▸ CA12 O43570 1/20 0.32
▸ CA9 Q16790 1/20 0.32
▸ BRD4 O60885 1/20 0.31
▸ GAA P10253 2/20 0.31
▸ NPSR1 Q6W5P4 2/20 0.31
▸ MAPK1 P28482 1/20 0.31
▸ ACACB O00763 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16429503 0.87 GRIN2D (0.38) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL18223045 0.85 SIGMAR1 (0.38) SIGMAR1
SCHEMBL16428997 0.84 NOS3 (0.35) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL16247194 0.81 MAOB (0.37) SIGMAR1
SCHEMBL16428941 0.81 SIGMAR1 (0.43) MEN1KMT2ASIGMAR1
SCHEMBL16429473 0.80 CARM1 (0.41) PRMT3CARM1PRMT6PRMT1PRMT8
Hydrochloric Acid SCHEMBL16247175 0.80 SIGMAR1 (0.42) MEN1KMT2ASIGMAR1
SCHEMBL16264660 0.79 CARM1 (0.50) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL18223038 0.79 SIGMAR1 (0.38) MEN1KMT2ASIGMAR1CA12CA9
SCHEMBL16429460 0.79 PRKCD (0.36) PRMT6SIGMAR1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10440955-B2 Methods comprising a biocidal polyamine CURZA GLOBAL, LLC (US) 2019-10-15 — — US disclosed
US-20180125070-A1 COMPOSITIONS AND METHODS COMPRISING A BIOCIDAL POLYAMINE THE UNIVERSITY OF UTAH 2018-05-10 — — US disclosed
US-9839219-B2 Compositions comprising a biocidal polyamine CURZA GLOBAL, LLC (US) 2017-12-12 — — US disclosed
US-20160330962-A1 COMPOSITIONS COMPRISING A BIOCIDAL POLYAMINE CURZA GLOBAL, LLC 2016-11-17 — — US disclosed
US-9439433-B2 Compositions and methods comprising a biocidal polyamine CURZA GLOBAL, LLC (US) 2016-09-13 — — US disclosed
US-20150038512-A1 COMPOSITIONS AND METHODS COMPRISING A BIOCIDAL POLYAMINE THE UNIVERSITY OF UTAH 2015-02-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160330962-A1 COMPOSITIONS COMPRISING A BIOCIDAL POLYAMINE SRM, SMS, SMOX PRMT3 32/4885CARM1 1018/4885PRMT6 141/4885
US-10440955-B2 Methods comprising a biocidal polyamine SRM, SMOX, SMS PRMT3 62/4885CARM1 1165/4885PRMT6 222/4885
US-20180125070-A1 COMPOSITIONS AND METHODS COMPRISING A BIOCIDAL POLYAMINE SRM, SMOX, SMS PRMT3 42/4885CARM1 943/4885PRMT6 176/4885
US-20150038512-A1 COMPOSITIONS AND METHODS COMPRISING A BIOCIDAL POLYAMINE SRM, SMOX, SMS PRMT3 42/4885CARM1 943/4885PRMT6 176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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