SCHEMBL16429473

SCHEMBL16429473

CC(C)Oc1ccc(-c2cc(CC(N)CCNCCCN)cc(CC(N)CCNCCCN)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ CARM1 Q86X55 3/20 0.41
▸ PRMT3 O60678 2/20 0.41
▸ PRMT6 Q96LA8 2/20 0.41
▸ PRMT1 Q99873 2/20 0.41
▸ PRMT8 Q9NR22 2/20 0.41
▸ NPSR1 Q6W5P4 3/20 0.35
▸ GAA P10253 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ MCL1 Q07820 4/20 0.34
▸ MEN1 O00255 8/20 0.34
▸ KMT2A Q03164 8/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ CYP2D6 P10635 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ MITF O75030 1/20 0.34
▸ ERN1 O75460 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ FFAR4 Q5NUL3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16429501 0.88 GRIN2D (0.38) CARM1PRMT3PRMT6PRMT1PRMT8
SCHEMBL18223044 0.85 MC4R (0.36) —
SCHEMBL16264660 0.83 CARM1 (0.50) CARM1PRMT3PRMT6PRMT1PRMT8
SCHEMBL16428992 0.82 MAOB (0.36) MEN1KMT2ACYP2D6CYP2C19
SCHEMBL16428940 0.81 MMP2 (0.40) —
Hydrochloric Acid SCHEMBL16246761 0.80 MMP2 (0.40) —
Hydrochloric Acid SCHEMBL16247177 0.80 MMP2 (0.40) —
SCHEMBL16429107 0.80 CHRNB2 (0.42) —
SCHEMBL16429474 0.80 PRMT3 (0.40) CARM1PRMT3PRMT6PRMT1PRMT8
SCHEMBL18223036 0.79 CA12 (0.43) MEN1KMT2ACYP2C19MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10440955-B2 Methods comprising a biocidal polyamine CURZA GLOBAL, LLC (US) 2019-10-15 — — US disclosed
US-20180125070-A1 COMPOSITIONS AND METHODS COMPRISING A BIOCIDAL POLYAMINE THE UNIVERSITY OF UTAH 2018-05-10 — — US disclosed
US-9839219-B2 Compositions comprising a biocidal polyamine CURZA GLOBAL, LLC (US) 2017-12-12 — — US disclosed
US-20160330962-A1 COMPOSITIONS COMPRISING A BIOCIDAL POLYAMINE CURZA GLOBAL, LLC 2016-11-17 — — US disclosed
US-9439433-B2 Compositions and methods comprising a biocidal polyamine CURZA GLOBAL, LLC (US) 2016-09-13 — — US disclosed
US-20150038512-A1 COMPOSITIONS AND METHODS COMPRISING A BIOCIDAL POLYAMINE THE UNIVERSITY OF UTAH 2015-02-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160330962-A1 COMPOSITIONS COMPRISING A BIOCIDAL POLYAMINE SRM, SMS, SMOX CARM1 1018/4885PRMT3 32/4885PRMT6 141/4885
US-10440955-B2 Methods comprising a biocidal polyamine SRM, SMOX, SMS CARM1 1165/4885PRMT3 62/4885PRMT6 222/4885
US-20180125070-A1 COMPOSITIONS AND METHODS COMPRISING A BIOCIDAL POLYAMINE SRM, SMOX, SMS CARM1 943/4885PRMT3 42/4885PRMT6 176/4885
US-20150038512-A1 COMPOSITIONS AND METHODS COMPRISING A BIOCIDAL POLYAMINE SRM, SMOX, SMS CARM1 943/4885PRMT3 42/4885PRMT6 176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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