Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17808356 | 1.00 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2KDM4EHPGDLMNA | |
| SCHEMBL16429550 | 0.98 | S100A4 (0.36) | ALDH1A1SMN1; SMN2KDM4EHPGDLMNA | |
| SCHEMBL16429341 | 0.91 | S100A4 (0.38) | ALDH1A1SMN1; SMN2KDM4EHPGDLMNA | |
| SCHEMBL15551462 | 0.86 | S100A4 (0.42) | ALDH1A1SMN1; SMN2KDM4EHPGDLMNA | |
| SCHEMBL29906291 | 0.86 | S100A4 (0.42) | ALDH1A1SMN1; SMN2KDM4EHPGDLMNA | |
| SCHEMBL9097659 | 0.83 | GPR3 (0.41) | ALDH1A1SMN1; SMN2KDM4EHPGDLMNA | |
| SCHEMBL17037118 | 0.75 | ALDH1A1 (0.42) | ALDH1A1HPGDMAPTRAB9ATNKS | |
| SCHEMBL18193053 | 0.75 | MAOA (0.37) | ALDH1A1SMN1; SMN2KDM4EHPGDGAA | |
| SCHEMBL16745385 | 0.71 | RAB9A (0.44) | ALDH1A1SMN1; SMN2KDM4EHPGDLMNA | |
| SCHEMBL16745399 | 0.71 | ESR2 (0.48) | ALDH1A1LMNAGAAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9876182-B2 | Thieno-containing compounds and processes and uses thereof | UNIVERSITY OF OREGON (US) | 2018-01-23 | — | — | US | disclosed |
| US-9876182-B2 | Thieno-containing compounds and processes and uses thereof | UNIVERSITY OF OREGON (US) | 2018-01-23 | — | — | US | disclosed |
| US-20160164011-A1 | THIENO-CONTAINING COMPOUNDS AND PROCESSES AND USES THEREOF | UNIVERSITY OF OREGON (US) | 2016-06-09 | — | — | US | disclosed |
| US-20160164011-A1 | THIENO-CONTAINING COMPOUNDS AND PROCESSES AND USES THEREOF | UNIVERSITY OF OREGON (US) | 2016-06-09 | — | — | US | disclosed |
| WO-2015013656-A2 | THIENO-CONTAINING COMPOUNDS AND PROCESSES AND USES THEREOF | UNIVERSITY OF OREGON (US) | 2015-01-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160164011-A1 | THIENO-CONTAINING COMPOUNDS AND PROCESSES AND USES THEREOF | TERT, TES, DDT | ALDH1A1 245/4885SMN1; SMN2 2733/4885KDM4E 1588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.