SCHEMBL16433985

SCHEMBL16433985

N#C/N=C1\c2ccccc2-c2cc3c(cc21)-c1ccc(-c2ccc(C(F)(F)F)cc2)cc1C3NC#N

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.32
P2RY14 Q15391 1/20 0.31
TDP2 O95551 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20824157 0.95 KIF11 (0.34) KIF11TDP2
SCHEMBL20824289 0.93
SCHEMBL20823386 0.91 KIF11 (0.32) KIF11
SCHEMBL15095669 0.88 NAAA (0.33) KIF11
SCHEMBL20823388 0.88
SCHEMBL16433793 0.84 RXRA (0.31)
SCHEMBL16433983 0.82 CTSS (0.32) KIF11
SCHEMBL16433962 0.80 TAAR1 (0.31)
SCHEMBL16433984 0.80 CYP3A4 (0.34)
SCHEMBL12198573 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10424740-B2 Compound, material for organic electroluminescence devices, organic electroluminescence device, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-09-24 US disclosed
US-20190088879-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICES, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2019-03-21 US disclosed
EP-2833700-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Sony Corporation (JP) 2015-02-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190088879-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICES, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC DEVICE PIEZO1, LEF1, L1CAM KIF11 1827/4885P2RY14 3063/4885TDP2 3791/4885
US-10424740-B2 Compound, material for organic electroluminescence devices, organic electroluminescence device, and electronic device PIEZO1, LEF1, L1CAM KIF11 1827/4885P2RY14 3063/4885TDP2 3791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.