Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16454876 | 0.86 | NPC1 (0.55) | PIK3CDPIK3CAPIK3CBKMT2ASMN1; SMN2 | |
| SCHEMBL16454878 | 0.81 | LMNA (0.51) | PIK3CDPIK3CAPIK3CBKMT2ASMN1; SMN2 | |
| SCHEMBL16454875 | 0.79 | KCNK3 (0.53) | PIK3CDPIK3CAPIK3CBKMT2ASMN1; SMN2 | |
| SCHEMBL16454828 | 0.77 | FADS1 (0.51) | KMT2ASMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL16454823 | 0.77 | NPC1 (0.55) | KMT2ASMN1; SMN2RAB9ANPC1MEN1 | |
| SCHEMBL8814916 | 0.77 | L3MBTL1 (0.80) | KMT2ASMN1; SMN2PKMGAAHTT | |
| SCHEMBL16454801 | 0.73 | MAPT (0.50) | KMT2ASMN1; SMN2RAB9ANPC1GAA | |
| SCHEMBL16454830 | 0.72 | MAPT (0.50) | PIK3CDPIK3CAPIK3CBSMN1; SMN2RAB9A | |
| SCHEMBL16454787 | 0.72 | SMO (0.54) | KMT2ASMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL259421 | 0.71 | KCNK3 (0.86) | KMT2ASMN1; SMN2PKMRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015020565-A1 | SUBSTITUTED [1,2,4]TRIAZOLO[4,3-A]PYRIDINES EXHIBITING ANTAGONIST PROPERTIES TO ADENOSINE A2A RECEPTORS, AND USE THEREOF | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НЬЮВАК" (ООО "НЬЮВАК") (RU) | 2015-02-12 | — | — | WO | disclosed |