Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 6/20 | 0.40 |
| ▸ | RXRB | P28702 | 6/20 | 0.40 |
| ▸ | RXRG | P48443 | 5/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455817 | 0.87 | RXRA (0.41) | RXRARXRBRXRGKIF11PSEN1 | |
| SCHEMBL911318 | 0.76 | MGLL (0.35) | KIF11PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28564005 | 0.73 | ALDH1A1 (0.39) | TRPV6CNR1CNR2P2RX1TACR1 | |
| SCHEMBL4246248 | 0.72 | RXRA (0.31) | RXRARXRBRXRG | |
| SCHEMBL4251846 | 0.71 | ANPEP (0.30) | — | |
| SCHEMBL28419769 | 0.71 | KIF11 (0.40) | KIF11TRPV6PTPN1 | |
| SCHEMBL28222642 | 0.69 | KIF11 (0.70) | RXRARXRBRXRGKIF11BACE1 | |
| SCHEMBL8718917 | 0.69 | PDK2 (0.33) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL1901069 | 0.68 | CNR2 (0.38) | RXRARXRBRXRGTRPV6AKR1C3 | |
| SCHEMBL2138447 | 0.67 | KIF11 (0.65) | RXRARXRBRXRGKIF11BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140011971-A1 | IRON COMPLEXES AND METHODS FOR POLYMERIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-01-09 | — | — | US | disclosed |