Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CTH | P32929 | 1/20 | 0.31 |
| ▸ | CBS | P35520 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | CPT2 | P23786 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HMGCR | P04035 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26439795 | 0.93 | — | — | |
| SCHEMBL26439737 | 0.87 | — | — | |
| SCHEMBL12301946 | 0.83 | CES2 (0.44) | TSHRTDP1ALDH1A1 | |
| SCHEMBL1644006 | 0.82 | TSHR (0.36) | TSHRTDP1ALDH1A1 | |
| SCHEMBL22681405 | 0.82 | ALDH1A1 (0.36) | TSHRTDP1ALDH1A1THRB | |
| SCHEMBL15111048 | 0.80 | TSHR (0.35) | TSHRTDP1SMN1; SMN2EPHX2CTH | |
| SCHEMBL23482623 | 0.80 | EPHX2 (0.33) | SMN1; SMN2EPHX2PTGS1 | |
| SCHEMBL22389094 | 0.79 | TSHR (0.32) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL13368910 | 0.78 | VCAM1 (0.30) | — | |
| SCHEMBL13471978 | 0.77 | HMGCR (0.34) | TSHRTDP1EPHX2CYP2C19FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11234988-B2 | Fluorohydroxyproline derivatives useful in the preparation of proteolysis targeted chimeras | UNIVERSITY OF DUNDEE (GB) | 2022-02-01 | — | — | US | disclosed |
| EP-2307429-B1 | SUBSTITUTED BUTANOL DERIVATIVES AND THEIR USE AS FRAGRANCE AND FLAVOR MATERIALS | TAKASAGO PERFUMERY CO LTD (JP) | 2018-02-28 | — | — | EP | disclosed |
| EP-2307429-B1 | SUBSTITUTED BUTANOL DERIVATIVES AND THEIR USE AS FRAGRANCE AND FLAVOR MATERIALS | TAKASAGO PERFUMERY CO LTD (JP) | 2018-02-28 | — | — | EP | disclosed |
| US-20170367388-A1 | SUBSTITUTED BUTANOL DERIVATIVES AND THEIR USE AS FRAGRANCE AND FLAVOR MATERIALS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2017-12-28 | — | — | US | disclosed |
| US-20170367388-A1 | SUBSTITUTED BUTANOL DERIVATIVES AND THEIR USE AS FRAGRANCE AND FLAVOR MATERIALS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2017-12-28 | — | — | US | disclosed |
| US-9756872-B2 | Substituted butanol derivatives and their use as fragrance and flavor materials | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2017-09-12 | — | — | US | disclosed |
| US-9756872-B2 | Substituted butanol derivatives and their use as fragrance and flavor materials | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2017-09-12 | — | — | US | disclosed |
| US-9756872-B2 | Substituted butanol derivatives and their use as fragrance and flavor materials | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2017-09-12 | — | — | US | disclosed |
| US-20150245641-A1 | SUBSTITUTED BUTANOL DERIVATIVES AND THEIR USE AS FRAGRANCE AND FLAVOR MATERIALS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2015-09-03 | — | — | US | disclosed |
| US-20150245641-A1 | SUBSTITUTED BUTANOL DERIVATIVES AND THEIR USE AS FRAGRANCE AND FLAVOR MATERIALS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2015-09-03 | — | — | US | disclosed |
| EP-2279754-B1 | Remodelling and glycoconjugation of human growth hormone (hGH) | RATIOPHARM GMBH (DE) | 2014-08-13 | — | — | EP | disclosed |
| EP-2298354-B1 | Remodelling and glycoconjugation of interferon-beta | RATIOPHARM GMBH (DE) | 2014-03-19 | — | — | EP | disclosed |
| US-20110217245-A1 | Substituted Butanol Derivatives And Their Use As Fragrance And Flavor Materials | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-09-08 | — | — | US | disclosed |
| US-20110217245-A1 | Substituted Butanol Derivatives And Their Use As Fragrance And Flavor Materials | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-09-08 | — | — | US | disclosed |
| US-20110217245-A1 | Substituted Butanol Derivatives And Their Use As Fragrance And Flavor Materials | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-09-08 | — | — | US | disclosed |
| EP-2307429-A1 | SUBSTITUTED BUTANOL DERIVATIVES AND THEIR USE AS FRAGRANCE AND FLAVOR MATERIALS | Takasago International Corporation (JP) | 2011-04-13 | — | — | EP | disclosed |
| WO-2010002386-A1 | SUBSTITUTED BUTANOL DERIVATIVES AND THEIR USE AS FRAGRANCE AND FLAVOR MATERIALS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-01-07 | — | — | WO | disclosed |
| US-6969712-B2 | Benzimidazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-11-29 | — | — | US | disclosed |
| US-20040044056-A1 | Benzimidazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-04 | — | — | US | disclosed |
| EP-1342717-A1 | BENZIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2003-09-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170367388-A1 | SUBSTITUTED BUTANOL DERIVATIVES AND THEIR USE AS FRAGRANCE AND FLAVOR MATERIALS | ACMSD, C1S, C5 | TSHR 3468/4885TDP1 4134/4885ALDH1A1 1081/4885 |
| US-20110217245-A1 | Substituted Butanol Derivatives And Their Use As Fragrance And Flavor Materials | ACMSD, C1S, C5 | TSHR 3468/4885TDP1 4134/4885ALDH1A1 1081/4885 |
| US-20040044056-A1 | Benzimidazole derivatives | GPR119, OPRL1, INSR | TSHR 239/4885TDP1 2943/4885ALDH1A1 1851/4885 |
| US-11234988-B2 | Fluorohydroxyproline derivatives useful in the preparation of proteolysis targeted chimeras | RNF114, CUL1, MDM2 | TSHR 3242/4885TDP1 1942/4885ALDH1A1 4000/4885 |
| US-20150245641-A1 | SUBSTITUTED BUTANOL DERIVATIVES AND THEIR USE AS FRAGRANCE AND FLAVOR MATERIALS | ACMSD, C1S, C5 | TSHR 3468/4885TDP1 4134/4885ALDH1A1 1081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.