SCHEMBL1646276

SCHEMBL1646276

CCSSc1c(Br)cc(Br)cc1Br

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
FBP1 P09467 1/20 0.31
TXN P10599 1/20 0.31
GABRA1 P14867 1/20 0.30
GABRB1 P18505 1/20 0.30
GABRA2 P47869 1/20 0.30
GABRB2 P47870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1647439 0.78 NMT1 (0.32)
SCHEMBL1647001 0.77 CA2 (0.32) TDP1FBP1TXN
SCHEMBL4637268 0.77 TSHR (0.45) CYP3A4TSHRTDP1GABRA1GABRB1
SCHEMBL1645351 0.74 FBP1 (0.32) FBP1
SCHEMBL1647130 0.74
SCHEMBL1648131 0.72 ALOX15 (0.35) TSHRTDP1
SCHEMBL1647348 0.70 FBP1 (0.31) FBP1TXN
SCHEMBL1648209 0.65 CYP3A4 (0.35) CYP3A4TSHRTDP1GABRA1GABRB1
SCHEMBL1646234 0.65 MAOA (0.41) TSHRFBP1TXN
SCHEMBL1648006 0.64 ALDH1A1 (0.36) CYP3A4TSHRTDP1FBP1TXN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426526-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2013-04-23 US disclosed
US-20110086727-A1 SOLID GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2011-04-14 US disclosed