Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | PPARG | P37231 | 3/20 | 0.67 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.67 |
| ▸ | RXRA | P19793 | 2/20 | 0.67 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.67 |
| ▸ | F7 | P08709 | 3/20 | 0.57 |
| ▸ | F3 | P13726 | 3/20 | 0.57 |
| ▸ | PPARA | Q07869 | 3/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | PPARD | Q03181 | 2/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15678968 | 1.00 | ALDH1A1 (0.67) | ALDH1A1CYP19A1MAPTPPARGOXER1 | |
| SCHEMBL15241269 | 0.93 | ALDH1A1 (0.56) | ALDH1A1CYP19A1MAPTPPARGOXER1 | |
| SCHEMBL4708110 | 0.93 | ALDH1A1 (0.56) | ALDH1A1CYP19A1MAPTPPARGOXER1 | |
| SCHEMBL4708111 | 0.93 | ALDH1A1 (0.56) | ALDH1A1CYP19A1MAPTPPARGOXER1 | |
| SCHEMBL353830 | 0.91 | ALDH1A1 (0.72) | ALDH1A1CYP19A1MAPTPPARGOXER1 | |
| SCHEMBL353829 | 0.91 | ALDH1A1 (0.72) | ALDH1A1CYP19A1MAPTPPARGOXER1 | |
| SCHEMBL16596923 | 0.88 | ALDH1A1 (0.69) | ALDH1A1CYP19A1MAPTPPARGOXER1 | |
| SCHEMBL18250668 | 0.88 | ALDH1A1 (0.69) | ALDH1A1CYP19A1MAPTPPARGOXER1 | |
| SCHEMBL22645185 | 0.84 | ALDH1A1 (0.71) | ALDH1A1CYP19A1MAPTPPARGOXER1 | |
| SCHEMBL4553010 | 0.83 | ALDH1A1 (0.50) | ALDH1A1CYP19A1MAPTPPARGOXER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200038342-A1 | FATTY ACID CYSTEAMINE CONJUGATES AND THEIR USE AS ACTIVATORS OF AUTOPHAGY | CATABASIS PHARMACEUTICALS, INC. | 2020-02-06 | — | — | US | disclosed |
| US-10251845-B2 | Fatty acid cysteamine conjugates and their use as activators of autophagy | CATABASIS PHARMACEUTICALS, INC. (US) | 2019-04-09 | — | — | US | disclosed |
| US-20170258741-A1 | FATTY ACID CYSTEAMINE CONJUGATES AND THEIR USE AS ACTIVATORS OF AUTOPHAGY | CATABASIS PHARMACEUTICALS, INC. (US) | 2017-09-14 | — | — | US | disclosed |
| US-20140012024-A1 | METHOD FOR THE SYNTHESIS OF DHA | PHENOMENOME DISCOVERIES INC. (CA) | 2014-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140012024-A1 | METHOD FOR THE SYNTHESIS OF DHA | FADS2, FASN, ALOX5 | ALDH1A1 642/4885CYP19A1 222/4885MAPT 4553/4885 |
| US-20170258741-A1 | FATTY ACID CYSTEAMINE CONJUGATES AND THEIR USE AS ACTIVATORS OF AUTOPHAGY | NDUFAB1, ATG7, HADHA | ALDH1A1 1342/4885CYP19A1 3419/4885MAPT 1528/4885 |
| US-10251845-B2 | Fatty acid cysteamine conjugates and their use as activators of autophagy | NDUFAB1, ATG7, NLN | ALDH1A1 1672/4885CYP19A1 3834/4885MAPT 1391/4885 |
| US-20200038342-A1 | FATTY ACID CYSTEAMINE CONJUGATES AND THEIR USE AS ACTIVATORS OF AUTOPHAGY | ATG7, ATG4A, SLC27A1 | ALDH1A1 2685/4885CYP19A1 1934/4885MAPT 1391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.