Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.83 |
| ▸ | HPGD | P15428 | 4/20 | 0.83 |
| ▸ | NPC1 | O15118 | 3/20 | 0.83 |
| ▸ | RAB9A | P51151 | 3/20 | 0.83 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.83 |
| ▸ | CASP3 | P42574 | 1/20 | 0.83 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.83 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.83 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.83 |
| ▸ | MAOA | P21397 | 3/20 | 0.71 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.62 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.62 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1567209 | 0.93 | MAOA (0.86) | MAPTKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL28401540 | 0.92 | NPC1 (0.76) | MAPTKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL11726836 | 0.92 | ALDH1A1 (0.71) | MAPTKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL2161251 | 0.91 | ALDH1A1 (1.00) | MAPTKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL29619913 | 0.91 | ALDH1A1 (1.00) | MAPTKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL20317284 | 0.88 | KDM4E (0.69) | MAPTKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL20317282 | 0.88 | KDM4E (0.69) | MAPTKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL20346707 | 0.88 | MAPT (0.65) | MAPTKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL1611070 | 0.86 | ALPG (0.59) | MAPTKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL7331388 | 0.85 | KDM4E (0.86) | MAPTKDM4EALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220251106-A1 | ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE | CANON KABUSHIKI KAISHA (JP) | 2022-08-11 | — | — | US | disclosed |
| US-9163002-B2 | Methodology for the synthesis of xanthones | UNIVERSITY OF SOUTH CAROLINA (US) | 2015-10-20 | — | — | US | disclosed |
| US-9163002-B2 | Methodology for the synthesis of xanthones | UNIVERSITY OF SOUTH CAROLINA (US) | 2015-10-20 | — | — | US | disclosed |
| US-20140107354-A1 | New Methodology for the Synthesis of Xanthones | UNIVERSITY OF SOUTH CAROLINA | 2014-04-17 | — | — | US | disclosed |
| US-20140107354-A1 | New Methodology for the Synthesis of Xanthones | UNIVERSITY OF SOUTH CAROLINA | 2014-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107354-A1 | New Methodology for the Synthesis of Xanthones | XDH, TYR, NISCH | MAPT 2203/4885KDM4E 1101/4885ALDH1A1 857/4885 |
| US-20220251106-A1 | ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE | OR51E2, TAS2R38, SOD1 | MAPT 2879/4885KDM4E 4454/4885ALDH1A1 1459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.