Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16477975 | 0.95 | PPARG (0.33) | PPARGPPARARAB9A | |
| SCHEMBL16477964 | 0.90 | — | — | |
| SCHEMBL16477966 | 0.87 | PTPN11 (0.36) | — | |
| SCHEMBL17452488 | 0.86 | — | — | |
| SCHEMBL18012817 | 0.82 | PDK2 (0.36) | PPARGPPARARAB9A | |
| SCHEMBL16477961 | 0.80 | RAB9A (0.40) | THRATHRBRAB9A | |
| SCHEMBL17056201 | 0.80 | PDK2 (0.41) | PPARGPPARA | |
| SCHEMBL16477977 | 0.79 | THRA (0.36) | THRATHRBRAB9A | |
| SCHEMBL16477955 | 0.79 | — | — | |
| SCHEMBL16556664 | 0.78 | PDK2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382259-B2 | Compounds with oxime ester and/or acyl groups | AMERICAN DYE SOURCE, INC. (CA) | 2016-07-05 | — | — | US | disclosed |
| US-20160016964-A1 | Compounds With Oxime Ester And/Or Acyl Groups | AMERICAN DYE SOURCE, INC. (CA) | 2016-01-21 | — | — | US | disclosed |
| US-9127017-B2 | Compounds with oxime ester and/or acyl groups | AMERICAN DYE SOURCE, INC. (CA) | 2015-09-08 | — | — | US | disclosed |
| US-20140200350-A1 | COMPOUNDS WITH OXIME ESTER AND/OR ACYL GROUPS | AMERICAN DYE SOURCE, INC. (CA) | 2014-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200350-A1 | COMPOUNDS WITH OXIME ESTER AND/OR ACYL GROUPS | PPOX, SCO2, LPO | THRA 1594/4885THRB 1282/4885PPARG 277/4885 |
| US-20160016964-A1 | Compounds With Oxime Ester And/Or Acyl Groups | SCO2, PPOX, SQOR | THRA 1581/4885THRB 1317/4885PPARG 318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.