Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16486761 | 1.00 | USP30 (0.37) | USP30FAAHFFAR2SSTR4AAK1 | |
| SCHEMBL4154644 | 0.76 | PAX8 (0.35) | USP30FAAHSSTR4AAK1 | |
| SCHEMBL28337730 | 0.75 | FAAH (0.34) | USP30FAAHSSTR4AAK1 | |
| SCHEMBL7340517 | 0.74 | USP30 (0.37) | USP30 | |
| SCHEMBL8539792 | 0.71 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL29245714 | 0.70 | TRPM8 (0.37) | FAAHSSTR4 | |
| SCHEMBL30366914 | 0.69 | TRPM8 (0.36) | FAAHSSTR4 | |
| SCHEMBL3989548 | 0.69 | KMT2A (0.40) | — | |
| SCHEMBL6295154 | 0.69 | SLC6A3 (0.34) | USP30 | |
| SCHEMBL2791434 | 0.69 | SMN1; SMN2 (0.39) | USP30AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3145944-A2 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX Pharmaceuticals, Inc. (US) | 2017-03-29 | — | — | EP | disclosed |
| EP-3033352-A1 | LINEAR PEPTIDE ANTIBIOTICS | RQX Pharmaceuticals, Inc. (US) | 2016-06-22 | — | — | EP | disclosed |
| WO-2015179441-A2 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS, INC. (US) | 2015-11-26 | — | — | WO | disclosed |
| WO-2015023898-A1 | LINEAR PEPTIDE ANTIBIOTCS | RQX PHARMACEUTICALS, INC. (US) | 2015-02-19 | — | — | WO | disclosed |