Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2791434 | 0.85 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1LMNATSHRTDP1 | |
| SCHEMBL3989548 | 0.85 | KMT2A (0.40) | ALDH1A1LMNATSHRMEN1KMT2A | |
| SCHEMBL2791431 | 0.85 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1LMNATSHRTDP1 | |
| SCHEMBL4324062 | 0.84 | TRPM8 (0.40) | SMN1; SMN2ALDH1A1LMNATP53TRPM8 | |
| SCHEMBL4324066 | 0.84 | TRPM8 (0.40) | SMN1; SMN2ALDH1A1LMNATP53TRPM8 | |
| SCHEMBL7630006 | 0.84 | ALOX5 (0.47) | LMNAL3MBTL1 | |
| SCHEMBL1643846 | 0.84 | SLC6A2 (0.39) | SMN1; SMN2ALDH1A1CYP2C19NPSR1CHRNB2 | |
| SCHEMBL2174292 | 0.84 | AAK1 (0.36) | SMN1; SMN2ALDH1A1LMNATDP1MEN1 | |
| SCHEMBL7447861 | 0.84 | MEN1 (0.40) | SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL4381548 | 0.83 | GPR119 (0.35) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670305-B1 | PROCESS FOR PRODUCING 3-AMINO-2-HYDROXY-1-PROPANOL DERIVATIVE | KANEKA CORP (JP) | 1998-05-20 | — | — | EP | claimed |
| EP-0670305-A1 | PROCESS FOR PRODUCING 3-AMINO-2-HYDROXY-1-PROPANOL DERIVATIVE | KANEKA CORPORATION (JP) | 1995-09-06 | — | — | EP | claimed |
| US-4803292-A | Process for producing statin and related compounds | SUNTORY LIMITED (JP) | 1989-02-07 | — | — | US | disclosed |