Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.34 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.34 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2791431 | 0.86 | SMN1; SMN2 (0.39) | KMT2AMEN1ALDH1A1MAPTTSHR | |
| SCHEMBL6295154 | 0.86 | SLC6A3 (0.34) | KMT2AMEN1CTSK | |
| SCHEMBL2791434 | 0.86 | SMN1; SMN2 (0.39) | KMT2AMEN1ALDH1A1MAPTTSHR | |
| SCHEMBL8539792 | 0.85 | SMN1; SMN2 (0.40) | KMT2AMEN1ALDH1A1TSHRLMNA | |
| SCHEMBL4324066 | 0.84 | TRPM8 (0.40) | ALDH1A1MAPTTSHRLMNANPSR1 | |
| SCHEMBL4324062 | 0.84 | TRPM8 (0.40) | ALDH1A1MAPTTSHRLMNANPSR1 | |
| SCHEMBL4381548 | 0.83 | GPR119 (0.35) | ALDH1A1MAPT | |
| SCHEMBL4381546 | 0.83 | GPR119 (0.35) | ALDH1A1MAPT | |
| SCHEMBL10521236 | 0.81 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1MAPTTSHR | |
| SCHEMBL5846260 | 0.81 | KMT2A (0.40) | KMT2AMEN1KCNQ4KCNQ5MDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553969-B1 | Substituted phenethylamine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-06-30 | — | — | US | disclosed |
| EP-1149843-A1 | SUBSTITUTED PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-10-31 | — | — | EP | disclosed |