Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16495228 | 0.78 | ALDH1A1 (0.33) | L3MBTL1MAPTMT-CO2ALOX5 | |
| SCHEMBL16494855 | 0.75 | MT-CO2 (0.34) | L3MBTL1MAPTMT-CO2ALOX5 | |
| SCHEMBL1004976 | 0.69 | ALDH1A1 (0.52) | L3MBTL1MAPT | |
| SCHEMBL16495148 | 0.69 | BRD4 (0.40) | L3MBTL1MAPT | |
| SCHEMBL22207271 | 0.69 | MAPT (0.37) | MAPT | |
| SCHEMBL6893472 | 0.68 | L3MBTL1 (0.39) | L3MBTL1MAPT | |
| SCHEMBL18556394 | 0.68 | L3MBTL1 (0.39) | L3MBTL1MAPT | |
| SCHEMBL16495292 | 0.68 | PKM (0.44) | L3MBTL1MT-CO2ALOX5 | |
| SCHEMBL9259573 | 0.62 | MAPT (0.38) | MAPTACE | |
| SCHEMBL9260960 | 0.60 | MAPT (0.36) | MAPTACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2526945-A1 | New CRTH2 Antagonists | Almirall, S.A. (ES) | 2012-11-28 | — | — | EP | disclosed |