Trimeperidine

Trimeperidine

SCHEMBL1649689

CCC(=O)OC1(c2ccccc2)C[C@H](C)N(C)C[C@H]1C

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 4/20 0.76
OPRD1 P41143 4/20 0.76
MEN1 O00255 1/20 0.76
KMT2A Q03164 1/20 0.76
LMNA P02545 2/20 0.66
ALDH1A1 P00352 1/20 0.62
OPRK1 P41145 3/20 0.62
DRD3 P35462 2/20 0.57
NPSR1 Q6W5P4 1/20 0.44
GAA P10253 2/20 0.43
MAPT P10636 1/20 0.42
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trimeperidine SCHEMBL25235 1.00 OPRM1 (0.76) OPRM1OPRD1MEN1KMT2ALMNA
Trimeperidine SCHEMBL25236 1.00 OPRM1 (0.76) OPRM1OPRD1MEN1KMT2ALMNA
Trimeperidine SCHEMBL9420815 0.99 OPRM1 (0.78) OPRM1OPRD1MEN1KMT2ALMNA
Proheptazine SCHEMBL7618840 0.89 LMNA (0.72) OPRM1OPRD1MEN1KMT2ALMNA
SCHEMBL3704187 0.82 OPRM1 (0.54) OPRM1OPRD1MEN1KMT2ALMNA
SCHEMBL3707956 0.82 ALDH1A1 (0.57) OPRM1OPRD1MEN1KMT2ALMNA
Betaprodine SCHEMBL186644 0.81 LMNA (0.97) OPRM1OPRD1MEN1KMT2ALMNA
Betaprodine SCHEMBL248367 0.81 LMNA (0.97) OPRM1OPRD1MEN1KMT2ALMNA
Betaprodine SCHEMBL25053 0.81 LMNA (0.97) OPRM1OPRD1MEN1KMT2ALMNA
Alphaprodine SCHEMBL25054 0.81 LMNA (0.97) OPRM1OPRD1MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119816491-A New spirocyclohexane derivatives, pharmaceutical compositions containing them and their use as anti-apoptotic inhibitors 法国施维雅药厂 2025-04-11 CN disclosed
US-7927613-B2 Pharmaceutical co-crystal compositions UNIVERSITY OF SOUTH FLORIDA (US) 2011-04-19 US disclosed
US-7790905-B2 Pharmaceutical propylene glycol solvate compositions MCNEIL-PPC, INC. (US) 2010-09-07 US disclosed