Betaprodine

Betaprodine

SCHEMBL186644

CCC(=O)O[C@]1(c2ccccc2)CCN(C)C[C@H]1C

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.97
DRD3 P35462 2/20 0.69
NPSR1 Q6W5P4 1/20 0.60
OPRM1 P35372 6/20 0.57
OPRD1 P41143 5/20 0.57
OPRK1 P41145 4/20 0.57
KMT2A Q03164 2/20 0.52
MEN1 O00255 1/20 0.52
MAPK1 P28482 1/20 0.51
ALDH1A1 P00352 2/20 0.49
GAA P10253 1/20 0.48
SLC22A1 O15245 1/20 0.46
SLC6A4 P31645 1/20 0.46
ADRA1A P35348 1/20 0.46
KCNH2 Q12809 1/20 0.46
MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Betaprodine SCHEMBL25053 1.00 LMNA (0.97) LMNADRD3NPSR1OPRM1OPRD1
Betaprodine SCHEMBL248367 1.00 LMNA (0.97) LMNADRD3NPSR1OPRM1OPRD1
Alphaprodine SCHEMBL25054 1.00 LMNA (0.97) LMNADRD3NPSR1OPRM1OPRD1
Betaprodine SCHEMBL394431 0.99 LMNA (1.00) LMNADRD3NPSR1OPRM1OPRD1
Alphaprodine SCHEMBL8818643 0.99 LMNA (1.00) LMNADRD3NPSR1OPRM1OPRD1
Betaprodine SCHEMBL1649307 0.97 LMNA (0.93) LMNADRD3NPSR1OPRM1OPRD1
Proheptazine SCHEMBL25539 0.93 LMNA (0.84) LMNADRD3NPSR1OPRM1OPRD1
SCHEMBL11383571 0.89 LMNA (0.78) LMNADRD3NPSR1OPRM1OPRD1
Betaprodine SCHEMBL4283575 0.88 LMNA (0.77) LMNADRD3NPSR1OPRM1OPRD1
SCHEMBL8977860 0.88 LMNA (0.77) LMNADRD3NPSR1OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1362 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250228771-A1 ALKALINE INTRAORAL PRODUCTS EMPLICURE AB (publ) (SE) 2025-07-17 US claimed
EP-4565202-A1 ALKALINE INTRAORAL PRODUCTS EMPLICURE AB (publ) (SE) 2025-06-11 EP claimed
US-20240288374-A1 PLASMONIC NANOPARTICLE PLATFORM FOR ANALYTE DETECTION Zymeron Corporation 2024-08-29 US claimed
WO-2024172892-A1 PLASMONIC NANOPARTICLE PLATFORM FOR ANALYTE DETECTION Zymeron Corporation (US) 2024-08-22 WO claimed
US-20240002395-A1 COMPOUNDS AND THEIR USE FOR TREATING NEUROPATHIC PAIN THE JOHNS HOPKINS UNIVERSITY 2024-01-04 US claimed
US-20230414702-A1 COMPOUNDS AND PHARMACEUTICAL USE THEREOF IN THE TREATMENT OF CANCER PEPKON SAS (FR) 2023-12-28 US claimed
EP-4255893-A1 COMPOUNDS AND THEIR USE FOR TREATING NEUROPATHIC PAIN The Johns Hopkins University (US) 2023-10-11 EP claimed
WO-2023187225-A1 ALKALINE INTRAORAL PRODUCTS AMPLICON AB (SE) 2023-10-05 WO claimed
US-11527315-B2 Drug device configured for wireless communication POP TEST ABUSE DETERRENT TECHNOLOGY LLC (US) 2022-12-13 US claimed
WO-2022119823-A1 COMPOUNDS AND THEIR USE FOR TREATING NEUROPATHIC PAIN THE JOHNS HOPKINS UNIVERSITY (US) 2022-06-09 WO claimed
US-20040254207-A1 Synergistic combinations including N-acylated 4-hydroxyphenylamine derivatives and caffeine NATIONAL SCIENCE FOUNDATION 2004-12-16 US claimed
WO-2004055003-A1 2-SUBSTITUTED QUINAZOLIN-4-YLAMINE ANALOGUES AS CAPSAICIN RECEPTOR MODULATORS NEUROGEN CORPORATION (US) 2004-07-01 WO claimed
WO-2004043460-A1 SYNERGISTIC COMBINATIONS WITH ANALGESIC PROPERTIES COMPRISING N-ACYLATED 4-HYDROXYPHENYLAMINE DERIVATIVES LSU MEDICAL CENTER FOUNDATION (US) 2004-05-27 WO claimed
US-20040092541-A1 SYNERGISTIC COMBINATIONS INCLUDING N-ACYLATED 4-HYDROYPHENYLAMINE DERIVATIVES NATIONAL SCIENCE FOUNDATION 2004-05-13 US claimed
US-20040052731-A1 Abuse-deterrent pharmaceutical compositions of opiods and other drugs COLLEGIUM PHARMACEUTICALS, INC. 2004-03-18 US claimed
WO-2004004693-A1 ABUSE-DETERRENT PHARMACEUTICAL COMPOSITIONS OF OPIODS AND OTHER DRUGS COLLGEGIUM PHARMACEUTICAL (US) 2004-01-15 WO claimed
EP-0608893-B1 Compositions for inhibiting the development of tolerance to and/or dependence on an additive substance UNIV VIRGINIA COMMONWEALTH (US) 2001-12-12 EP claimed
US-5654281-A Inhibiting the development of tolerance to and/or dependence on an addictive substance VIRGINIA COMMONWEALTH UNIVERSITY (US) 1997-08-05 US claimed
EP-0608893-A1 Inhibiting the development of tolerance to and/or dependence on an additive substance VIRGINIA COMMONWEALTH UNIVERSITY (US) 1994-08-03 EP claimed
US-4126684-A 4-AMINO-3-P-HALOPHENYLBUTYRIC ACIDS AND THEIR DERIVATIVES USED IN THE CONTROL OF NARCOTIC ABUSE CIBA-GEIGY CORPORATION (US) 1978-11-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11527315-B2 Drug device configured for wireless communication CYP2D6, CYP2B6, PTGDR LMNA 3860/4885DRD3 420/4885NPSR1 19/4885
US-20040254207-A1 Synergistic combinations including N-acylated 4-hydroxyphenylamine derivatives and caffeine OPRK1, OPRM1, OPRD1 LMNA 3906/4885DRD3 671/4885NPSR1 328/4885
US-20040092541-A1 SYNERGISTIC COMBINATIONS INCLUDING N-ACYLATED 4-HYDROYPHENYLAMINE DERIVATIVES OPRK1, OPRM1, OPRD1 LMNA 4660/4885DRD3 405/4885NPSR1 149/4885
US-20240002395-A1 COMPOUNDS AND THEIR USE FOR TREATING NEUROPATHIC PAIN MRGPRX1, MRGPRX4, MRGPRX2 LMNA 4368/4885DRD3 1269/4885NPSR1 117/4885
US-20230414702-A1 COMPOUNDS AND PHARMACEUTICAL USE THEREOF IN THE TREATMENT OF CANCER VIP, RNASE1, ABCB11 LMNA 4237/4885DRD3 4801/4885NPSR1 612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.