Trimeperidine

Trimeperidine

SCHEMBL25235

CCC(=O)O[C@@]1(c2ccccc2)C[C@H](C)N(C)C[C@H]1C

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 4/20 0.76
OPRD1 P41143 4/20 0.76
MEN1 O00255 1/20 0.76
KMT2A Q03164 1/20 0.76
LMNA P02545 2/20 0.66
ALDH1A1 P00352 1/20 0.62
OPRK1 P41145 3/20 0.62
DRD3 P35462 2/20 0.57
NPSR1 Q6W5P4 1/20 0.44
GAA P10253 2/20 0.43
MAPT P10636 1/20 0.42
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trimeperidine SCHEMBL1649689 1.00 OPRM1 (0.76) OPRM1OPRD1MEN1KMT2ALMNA
Trimeperidine SCHEMBL25236 1.00 OPRM1 (0.76) OPRM1OPRD1MEN1KMT2ALMNA
Trimeperidine SCHEMBL9420815 0.99 OPRM1 (0.78) OPRM1OPRD1MEN1KMT2ALMNA
Proheptazine SCHEMBL7618840 0.89 LMNA (0.72) OPRM1OPRD1MEN1KMT2ALMNA
SCHEMBL3704187 0.82 OPRM1 (0.54) OPRM1OPRD1MEN1KMT2ALMNA
SCHEMBL3707956 0.82 ALDH1A1 (0.57) OPRM1OPRD1MEN1KMT2ALMNA
Betaprodine SCHEMBL186644 0.81 LMNA (0.97) OPRM1OPRD1MEN1KMT2ALMNA
Betaprodine SCHEMBL248367 0.81 LMNA (0.97) OPRM1OPRD1MEN1KMT2ALMNA
Betaprodine SCHEMBL25053 0.81 LMNA (0.97) OPRM1OPRD1MEN1KMT2ALMNA
Alphaprodine SCHEMBL25054 0.81 LMNA (0.97) OPRM1OPRD1MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6886 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724049-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF Catalent Ontario Limited (CA) 2026-04-15 EP claimed
US-20250319074-A1 TREATMENT AND MANAGEMENT OF AUGMENTATION IN RESTLESS LEGS SYNDROME UNIV EAST CAROLINA (US) 2025-10-16 US claimed
US-12440489-B2 Organic compounds INTRA-CELLULAR THERAPIES, INC. (US) 2025-10-14 US claimed
US-12383743-B2 Treatment of addiction and dependency TACA JR ARTURO C (US) 2025-08-12 US claimed
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 EP claimed
WO-2024254056-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF CATALENT ONTARIO LIMITED (CA) 2024-12-12 WO claimed
US-12133922-B2 Abuse resistant capsule R.P. SCHERER TECHNOLOGIES, LLC (US) 2024-11-05 US claimed
US-20240343784-A1 TREATMENT OF MEDICATION OVERUSE HEADACHE USING ANTI-CGRP OR ANTI-CGRP-R ANTIBODIES H LUNDBECK AS (DK) 2024-10-17 US claimed
US-20240288374-A1 PLASMONIC NANOPARTICLE PLATFORM FOR ANALYTE DETECTION Zymeron Corporation 2024-08-29 US claimed
WO-2024172892-A1 PLASMONIC NANOPARTICLE PLATFORM FOR ANALYTE DETECTION Zymeron Corporation (US) 2024-08-22 WO claimed
US-5654281-A Inhibiting the development of tolerance to and/or dependence on an addictive substance VIRGINIA COMMONWEALTH UNIVERSITY (US) 1997-08-05 US claimed
EP-0785775-A1 MELT-EXTRUDED ORALLY ADMINISTRABLE OPIOID FORMULATIONS Euroceltique S.A. (LU) 1997-07-30 EP claimed
EP-0731694-A4 1996-10-02 EP claimed
EP-0731694-A1 OPIOID FORMULATIONS FOR TREATING PAIN Euroceltique S.A. (LU) 1996-09-18 EP claimed
CN-1130352-A Method for relieving pain by orally administering 24-hour sustained-release opioid dosage form capable of rapidly increasing initial blood concentration of patient EURO CELTIQUE SA (LU) 1996-09-04 CN claimed
WO-1996014058-A1 MELT-EXTRUDED ORALLY ADMINISTRABLE OPIOID FORMULATIONS EURO-CELTIQUE, S.A. (LU) 1996-05-17 WO claimed
WO-1995014460-A1 OPIOID FORMULATIONS FOR TREATING PAIN EURO-CELTIQUE S.A. (LU) 1995-06-01 WO claimed
EP-0647448-A1 Orally administrable opioid formulations having extended duration of effect Euroceltique S.A. (LU) 1995-04-12 EP claimed
EP-0608893-A1 Inhibiting the development of tolerance to and/or dependence on an additive substance VIRGINIA COMMONWEALTH UNIVERSITY (US) 1994-08-03 EP claimed
US-4126684-A 4-AMINO-3-P-HALOPHENYLBUTYRIC ACIDS AND THEIR DERIVATIVES USED IN THE CONTROL OF NARCOTIC ABUSE CIBA-GEIGY CORPORATION (US) 1978-11-21 US claimed