SCHEMBL165004

SCHEMBL165004

C=Cc1ccccc1C(F)(F)F

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 1/20 0.52
GRIN2D O15399 2/20 0.47
GRIN3B O60391 2/20 0.47
GRIN1 Q05586 2/20 0.47
GRIN2A Q12879 2/20 0.47
GRIN2B Q13224 2/20 0.47
GRIN2C Q14957 2/20 0.47
GRIN3A Q8TCU5 2/20 0.47
TNF P01375 2/20 0.46
IL6 P05231 1/20 0.46
ALDH1A1 P00352 3/20 0.44
MAOB P27338 4/20 0.43
P4HB P07237 1/20 0.42
ABCG2 Q9UNQ0 1/20 0.42
LMNA P02545 1/20 0.41
MYC P01106 1/20 0.40
MAX P61244 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29446986 1.00 NFKB1 (0.52) NFKB1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL21268025 0.87 NFKB1 (0.42) NFKB1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL4561525 0.84 NFKB1 (0.40) NFKB1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7083651 0.83 HSD11B1 (0.42) NFKB1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL29056471 0.82 ALDH1A1 (0.46) NFKB1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL5963736 0.80 NFKB1 (0.39) NFKB1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL453534 0.80 NFKB1 (0.39) NFKB1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL2494559 0.80 NFKB1 (0.55) NFKB1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL25090393 0.79 P2RX7 (0.44) NFKB1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL6853946 0.79 MEN1 (0.41) NFKB1GRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3607 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4419618-B1 FLUORESCENT BARCODED QUANTUM DOTS FOR DRILLING DEPTH CORRELATION SAUDI ARABIAN OIL CO (SA) 2026-05-13 EP claimed
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES ALCON INC (CH) 2026-01-01 US claimed
US-12379611-B2 Diffractive contact lenses ALCON INC. (CH) 2025-08-05 US claimed
US-12372503-B2 Multifunctional magnetic tags for mud logging SAUDI ARABIAN OIL COMPANY (SA) 2025-07-29 US claimed
CN-119264917-A Environment-friendly fluorine-containing surfactant, preparation method and application 浙江巨化技术中心有限公司 2025-01-07 CN claimed
EP-4419618-A1 FLUORESCENT BARCODED QUANTUM DOTS FOR DRILLING DEPTH CORRELATION Saudi Arabian Oil Company (SA) 2024-08-28 EP claimed
CN-118382683-A Fluorescent barcode quantum dots for well depth correlation 沙特阿拉伯石油公司 2024-07-23 CN claimed
CN-118336112-A Thermally responsive safety additive, composition for electrolyte, preparation method of electrolyte and battery 国网湖南省电力有限公司 2024-07-12 CN claimed
EP-4356169-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-04-24 EP claimed
CN-117855600-A Gel polymer electrolyte and application thereof 广州天赐高新材料股份有限公司 2024-04-09 CN claimed
WO-1998034113-A1 COMBINATORIAL LIBRARIES OF BICYCLIC GUANIDINE DERIVATIVES AND COMPOUNDS THEREIN TREGA BIOSCIENCES, INC. (US) 1998-08-06 WO claimed
WO-1998034112-A1 COMBINATORIAL LIBRARIES OF IMIDAZOL-PYRIDO-INDOLES AND IMIDAZOL-PYRIDO-BENZOTHIOPHENE DERIVATIVES TREGA BIOSCIENCES, INC. (US) 1998-08-06 WO claimed
WO-1998026886-A1 USE OF CO2-SOLUBLE MATERIALS AS TRANSIENT SPACERS, TEMPLATES, ADHESIVES, BINDERS, COATINGS AND MOLDS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1998-06-25 WO claimed
US-5610249-A FREE RADICAL CATALYST, ORGANIC PHOSPHORUS COMPOUND KANSAI PAINT CO., LTD. (JP) 1997-03-11 US claimed
US-4960768-A Acyloxythiophene-carboxamide fungicides BAYER AKTIENGESELLSCHAFT (DE) 1990-10-02 US claimed
US-4863954-A Acyloxythiophene-carboxamide fungicides BAYER AKTIENGESELLSCHAFT (DE) 1989-09-05 US claimed
EP-0241735-A2 Acyloxythiophene carbon amide BAYER AG (DE) 1987-10-21 EP claimed
US-4423089-A LATEX COPOLYMER CONSISTING OF DIOLEFIN, MONOVINYL MONOMER, AND POLYVINYL OR ACRYOYL MONOMER FUJI PHOTO FILM CO., LTD. (JP) 1983-12-27 US claimed
US-4420225-A Lens of a homo- or copolymer of a fluorine containing styrene polymer BAYER AKTIENGESELLSCHAFT (DE) 1983-12-13 US claimed
EP-0025159-A2 Use of styrene polymers for the preparation of optical system BAYER AG (DE) 1981-03-18 EP claimed