Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.39 |
| ▸ | ORAI2 | Q96SN7 | 3/20 | 0.39 |
| ▸ | ORAI3 | Q9BRQ5 | 3/20 | 0.39 |
| ▸ | TRPV6 | Q9H1D0 | 3/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4181226 | 0.79 | ALDH1A1 (0.46) | ALDH1A1ADRA2BPTGS1TDP1ORAI1 | |
| SCHEMBL29365322 | 0.79 | ALDH1A1 (0.50) | ALDH1A1ADRA2BPTGS1TDP1ORAI1 | |
| SCHEMBL1629992 | 0.79 | ALDH1A1 (0.50) | ALDH1A1ADRA2BPTGS1TDP1ORAI1 | |
| SCHEMBL28755480 | 0.78 | ENPP2 (0.34) | ALDH1A1ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL3228199 | 0.78 | CA2 (0.45) | ALDH1A1TDP1ORAI1ORAI2ORAI3 | |
| SCHEMBL28930064 | 0.77 | ALDH1A1 (0.48) | ALDH1A1ADRA2BPTGS1TDP1ORAI1 | |
| Hydrochloric Acid SCHEMBL28776334 | 0.77 | ALDH1A1 (0.48) | ALDH1A1ADRA2BPTGS1TDP1ORAI1 | |
| SCHEMBL28665189 | 0.77 | ALDH1A1 (0.48) | ALDH1A1ADRA2BPTGS1TDP1ORAI1 | |
| SCHEMBL28678398 | 0.77 | ALDH1A1 (0.48) | ALDH1A1ADRA2BPTGS1TDP1ORAI1 | |
| SCHEMBL969625 | 0.76 | ENPP2 (0.39) | ALDH1A1TDP1ORAI1ORAI2ORAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680306-B2 | Complexes and method for synthesis of group 6 organometallics, and use thereof in an olefin metathesis method | IFP Energies Nouvelles (FR) | 2014-03-25 | — | — | US | claimed |
| US-20110098496-A1 | NOVEL COMPLEXES AND METHOD FOR SYNTHESIS OF GROUP 6 ORGANOMETALLICS, AND USE THEREOF IN AN OLEFIN METATHESIS METHOD | IFP Energies Nouvelles (FR) | 2011-04-28 | — | — | US | claimed |
| US-8680306-B2 | Complexes and method for synthesis of group 6 organometallics, and use thereof in an olefin metathesis method | IFP Energies Nouvelles (FR) | 2014-03-25 | — | — | US | disclosed |
| US-20110098496-A1 | NOVEL COMPLEXES AND METHOD FOR SYNTHESIS OF GROUP 6 ORGANOMETALLICS, AND USE THEREOF IN AN OLEFIN METATHESIS METHOD | IFP Energies Nouvelles (FR) | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098496-A1 | NOVEL COMPLEXES AND METHOD FOR SYNTHESIS OF GROUP 6 ORGANOMETALLICS, AND USE THEREOF IN AN OLEFIN METATHESIS METHOD | BHMT2, BHMT, TST | ALDH1A1 2006/4885ADRA2B 4846/4885PTGS1 3070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.