Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.50 |
| ▸ | ADH1C | P00326 | 1/20 | 0.50 |
| ▸ | ADH1A | P07327 | 1/20 | 0.50 |
| ▸ | ADH7 | P40394 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | MATK | P42679 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | NEK4 | P51957 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.41 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.41 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.41 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8763600 | 0.85 | ADH1B (0.47) | ADH1BADH1CADH1AADH7NR1H4 | |
| SCHEMBL5990330 | 0.83 | ADH1B (0.46) | ADH1BADH1CADH1AADH7MAPT | |
| SCHEMBL2586904 | 0.83 | ADH1B (0.46) | ADH1BADH1CADH1AADH7NPC1 | |
| SCHEMBL3304927 | 0.83 | HDAC3 (0.49) | ADH1BADH1CADH1AADH7 | |
| SCHEMBL27199447 | 0.81 | ALKBH5 (0.49) | ROCK2CHEK2PRKACARPS6KB1AKT1 | |
| SCHEMBL30498104 | 0.81 | ALKBH5 (0.49) | ROCK2CHEK2PRKACARPS6KB1AKT1 | |
| SCHEMBL17503952 | 0.80 | ADH1B (0.43) | ADH1BADH1CADH1AADH7 | |
| SCHEMBL5990841 | 0.80 | HTR7 (0.47) | ADH1BADH1CADH1AADH7NPC1 | |
| SCHEMBL8763196 | 0.78 | ADH1B (0.76) | ADH1BADH1CADH1AADH7LMNA | |
| SCHEMBL31566 | 0.77 | ADH1B (0.61) | ADH1BADH1CADH1AADH7NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3608317-A1 | COMPOUNDS & METHODS FOR THE ENHANCED DEGRADATION OF TARGETED PROTEINS & OTHER POLYPEPTIDES BY AN E3 UBIQUITIN LIGASE | Yale University (US) | 2020-02-12 | — | — | EP | disclosed |
| US-20110294118-A1 | WATER SOLUBLE FLUORESCENT COMPOUNDS | BIOSEARCH TECHNOLOGIES, INC. (US) | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294118-A1 | WATER SOLUBLE FLUORESCENT COMPOUNDS | ABCG2, AQP1, AQP3 | ADH1B 1114/4885ADH1C 2272/4885ADH1A 1518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.