Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.46 |
| ▸ | ADH1C | P00326 | 1/20 | 0.46 |
| ▸ | ADH1A | P07327 | 1/20 | 0.46 |
| ▸ | ADH7 | P40394 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16508324 | 0.83 | ADH1B (0.50) | ADH1BADH1CADH1AADH7MAPT | |
| SCHEMBL5398523 | 0.83 | ADH1B (0.50) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5385065 | 0.81 | ADH1B (0.48) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL3304927 | 0.79 | HDAC3 (0.49) | ADH1BADH1CADH1AADH7HDAC3 | |
| SCHEMBL2723303 | 0.77 | ALDH1A1 (0.37) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL31672808 | 0.77 | HTR7 (0.42) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL9300840 | 0.77 | HTR7 (0.42) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL6904685 | 0.76 | SKP2 (0.37) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL8763600 | 0.76 | ADH1B (0.47) | ADH1BADH1CADH1AADH7KMT2A | |
| SCHEMBL17503952 | 0.76 | ADH1B (0.43) | ADH1BADH1CADH1AADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10364235-B2 | Insecticidal compounds | Synenta Crop Protection LLC (US) | 2019-07-30 | — | — | US | disclosed |
| US-10364235-B2 | Insecticidal compounds | Synenta Crop Protection LLC (US) | 2019-07-30 | — | — | US | disclosed |
| US-20180065956-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2018-03-08 | — | — | US | disclosed |
| US-20180065956-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2018-03-08 | — | — | US | disclosed |
| US-20180065956-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2018-03-08 | — | — | US | disclosed |
| US-9834546-B2 | Insecticidal compounds | SYNGENTA LIMITED (GB) | 2017-12-05 | — | — | US | disclosed |
| US-9834546-B2 | Insecticidal compounds | SYNGENTA LIMITED (GB) | 2017-12-05 | — | — | US | disclosed |
| US-9834546-B2 | Insecticidal compounds | SYNGENTA LIMITED (GB) | 2017-12-05 | — | — | US | disclosed |
| US-20170022187-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2017-01-26 | — | — | US | disclosed |
| US-20170022187-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2017-01-26 | — | — | US | disclosed |
| US-20130131137-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130131137-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130131137-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-05-23 | — | — | US | disclosed |
| CN-102803257-A | Insecticidal Compounds | SYNGENTA PARTICIPATIONS AG | 2012-11-28 | — | — | CN | disclosed |
| US-20110269804-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110269804-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110269804-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-11-03 | — | — | US | disclosed |
| CN-102131804-A | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG | 2011-07-20 | — | — | CN | disclosed |
| WO-2010149506-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-12-29 | — | — | WO | disclosed |
| WO-2010020522-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022187-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, NIT2 | ADH1B 1802/4885ADH1C 524/4885ADH1A 779/4885 |
| US-20130131137-A1 | INSECTICIDAL COMPOUNDS | F5, CHRM1, CHRM2 | ADH1B 2258/4885ADH1C 666/4885ADH1A 806/4885 |
| US-10364235-B2 | Insecticidal compounds | ACHE, CHRM1, NIT2 | ADH1B 1802/4885ADH1C 524/4885ADH1A 779/4885 |
| US-20180065956-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, NIT2 | ADH1B 1802/4885ADH1C 524/4885ADH1A 779/4885 |
| US-20110269804-A1 | INSECTICIDAL COMPOUNDS | CHRM1, CHRM2, C1R | ADH1B 2201/4885ADH1C 1180/4885ADH1A 2305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.