SCHEMBL165103

SCHEMBL165103

CCC(CC)C(=O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.44
MAPK1 P28482 1/20 0.44
SLC1A3 P43003 1/20 0.42
SLC1A2 P43004 1/20 0.42
SLC1A1 P43005 1/20 0.42
USP2 O75604 1/20 0.42
TSHR P16473 1/20 0.42
CHRM1 P11229 1/20 0.39
AKR1A1 P14550 1/20 0.39
CHRM3 P20309 1/20 0.39
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
ADRA1A P35348 1/20 0.39
HRH1 P35367 1/20 0.39
DRD3 P35462 1/20 0.39
SLC6A3 Q01959 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CA1 P00915 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9668057 0.84 MMP2 (0.40) CA2MAPK1SLC1A3SLC1A2SLC1A1
SCHEMBL3020928 0.84 CHRM1 (0.56) CA2MAPK1SLC1A3SLC1A2SLC1A1
SCHEMBL3014658 0.80 CA2 (0.68) CA2MAPK1SLC1A3SLC1A2SLC1A1
SCHEMBL30320036 0.80 GABRR1 (0.43) CA2MAPK1SLC1A3SLC1A2SLC1A1
SCHEMBL3018124 0.80 CA2 (0.36) CA2MAPK1SLC1A3SLC1A2SLC1A1
SCHEMBL1300143 0.80 FOLH1 (0.46) HDAC1HDAC2FFAR3
SCHEMBL17060892 0.78 CA2 (0.34) CA2MAPK1SLC1A3SLC1A2SLC1A1
SCHEMBL1539084 0.78 CA2 (0.34) CA2MAPK1SLC1A3SLC1A2SLC1A1
SCHEMBL3616152 0.77 CA2 (0.47) CA2MAPK1SLC1A3SLC1A2SLC1A1
SCHEMBL15656133 0.75 TSHR (0.42) CA2MAPK1SLC1A3SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020002138-A1 C5 OR C6 ACID ESTER-BASED CATALYST AND USE THEREOF IN A HYDROPROCESSING AND/OR HYDROCRACKING PROCESS IFP Energies Nouvelles (FR) 2020-01-02 WO claimed
US-20080233619-A1 Process For the Enantioselective Enzymatic Reduction of Keto Compounds IEP GMBH (DE) 2008-09-25 US claimed
EP-1635806-B1 METHOD FOR TREATING ALCOHOLIC HEPATITIS UNIV PITTSBURGH (US) 2008-05-28 EP claimed
EP-1233767-B1 PYRUVATE ESTER COMPOSITION AND METHOD OF USE FOR RESUSCITATION AFTER EVENTS OF ISCHEMIA AND REPERFUSION XANTHUS LIFE SCIENCES INC (CA) 2006-04-12 EP claimed
EP-1494659-B1 PHARMACEUTICAL COMPOSITION COMPRISING AN ALPHA-KETOALKANOIC ACID ESTER OR -AMIDE AND LACTIC ACID OR A LACTIC ACID SALT CRITICAL THERAPEUTICS INC (US) 2005-10-12 EP claimed
US-12417818-B1 Total mutational burden (TMB) estimate Ocean Genomics, Inc. (US) 2025-09-16 US disclosed
US-20240199611-A1 ANTIBACTERIAL COMPOUNDS Janssen Sciences Ireland Unlimited Company (IE) 2024-06-20 US disclosed
EP-4028399-B1 ANTIBACTERIAL COMPOUNDS JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) 2024-02-14 EP disclosed
EP-4308239-A1 ANTIBACTERIAL COMPOUNDS Janssen Sciences Ireland Unlimited Company (IE) 2024-01-24 EP disclosed
WO-2022228652-A1 MEANS AND METHOD FOR TREATING VIRAL INFECTIONS BIRKENMEIER GERD (DE) 2022-11-03 WO disclosed
US-20220340564-A1 ANTIBACTERIAL COMPOUNDS JANSSEN-CILAG (FR) 2022-10-27 US disclosed
WO-2022194803-A1 ANTIBACTERIAL COMPOUNDS Janssen Sciences Ireland Unlimited Company (IE) 2022-09-22 WO disclosed
WO-2005037788-A1 NOVEL METHOD FOR PREPARATION OF CRYSTALLINE PERINDOPRIL ERBUMINE LUPIN LTD. (IN) 2005-04-28 WO disclosed
EP-1509225-A1 METHOD FOR THE USE OF PYRANOINDOLE DERIVATIVES TO TREAT INFECTION WITH HEPATITIS C VIRUS Wyeth (US) 2005-03-02 EP disclosed
WO-2004075889-A1 PROCESS FOR PREPARATION OF PERINDOPRIL AND SALTS THEREOF LUPIN LIMITED (IN) 2004-09-10 WO disclosed
EP-1437401-A1 Oxidoreductase Juelich Enzyme Products GmbH (DE) 2004-07-14 EP disclosed
US-20040082643-A1 Method for the use of pyranoindole derivatives to treat infection with Hepatitis C virus WYETH (US) 2004-04-29 US disclosed
WO-2003099275-A1 METHOD FOR THE USE OF PYRANOINDOLE DERIVATIVES TO TREAT INFECTION WITH HEPATITIS C VIRUS WYETH (US) 2003-12-04 WO disclosed
EP-0739199-A1 ESTRADIOL PENETRATION INTENSIFIER FOR TRANSDERMAL ADMINISTRATION LTS LOHMANN Therapie-Systeme GmbH (DE) 1996-10-30 EP disclosed
WO-1995019162-A1 ESTRADIOL PENETRATION INTENSIFIER FOR TRANSDERMAL ADMINISTRATION LTS LOHMANN THERAPIE-SYSTEME GMBH & CO. KG (DE) 1995-07-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199611-A1 ANTIBACTERIAL COMPOUNDS FDPS, MT-ND4, NDUFS3 CA2 3021/4885MAPK1 3767/4885SLC1A3 4692/4885
US-20040082643-A1 Method for the use of pyranoindole derivatives to treat infection with Hepatitis C virus HAVCR2, HCCS, ZC3HAV1 CA2 4572/4885MAPK1 2864/4885SLC1A3 2691/4885
US-20220340564-A1 ANTIBACTERIAL COMPOUNDS FDPS, SQOR, NDUFS3 CA2 3368/4885MAPK1 3763/4885SLC1A3 4655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.