Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 4/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.35 |
| ▸ | ITGAL | P20701 | 2/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | PTPRA | P18433 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | GGH | Q92820 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16561804 | 0.78 | CYP1A2 (0.44) | PTPN1 | |
| SCHEMBL15708508 | 0.75 | PTPRA (0.61) | FDPSPTPRAGPR132 | |
| SCHEMBL16561817 | 0.74 | FDPS (0.40) | FDPSPTPRA | |
| SCHEMBL17933370 | 0.72 | FDPS (0.38) | FDPS | |
| SCHEMBL17933334 | 0.71 | FDPS (0.36) | FDPSPTPN1 | |
| SCHEMBL17925378 | 0.70 | ITGB3 (0.43) | ITGB1ITGB3ITGAVPTPN1ITGA4 | |
| SCHEMBL16554003 | 0.68 | ITGB1 (0.35) | ITGB1ITGA5L3MBTL1PTPN1GGH | |
| Hydrochloric Acid SCHEMBL28981170 | 0.67 | CA2 (0.34) | FDPS | |
| SCHEMBL16553693 | 0.67 | GRN (0.36) | GGH | |
| SCHEMBL11915445 | 0.66 | PPARA (0.50) | ITGB3PTPN1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10053476-B2 | Phosphohistidine and phosphotyrosine analogues | UNIVERSITY OF SHEFFIELD (GB) | 2018-08-21 | — | — | US | disclosed |
| EP-2976346-B1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | UNIV SHEFFIELD (GB) | 2017-02-22 | — | — | EP | disclosed |
| US-20160207948-A1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | UNIVERSITY OF SHEFFIELD (GB) | 2016-07-21 | — | — | US | disclosed |
| EP-2976346-A1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | University of Sheffield (GB) | 2016-01-27 | — | — | EP | disclosed |
| WO-2015033120-A1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | UNIVERSITY OF SHEFFIELD (GB) | 2015-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160207948-A1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | HRH3, CYTH3, CYTH2 | ITGB1 1599/4885ITGA5 322/4885ITGB3 1279/4885 |
| US-10053476-B2 | Phosphohistidine and phosphotyrosine analogues | HRH3, CYTH3, CYTH2 | ITGB1 1746/4885ITGA5 362/4885ITGB3 1446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.