Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL234642 | 0.92 | OPRM1 (0.52) | ALDH1A1SMN1; SMN2OPRM1LMNATSHR | |
| SCHEMBL1657137 | 0.89 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2OPRM1LMNATSHR | |
| SCHEMBL3185161 | 0.85 | DNM1 (0.47) | ALDH1A1SMN1; SMN2OPRM1LMNATSHR | |
| SCHEMBL22345156 | 0.85 | DNM1 (0.47) | ALDH1A1SMN1; SMN2OPRM1LMNATSHR | |
| SCHEMBL1051731 | 0.83 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2OPRM1LMNATSHR | |
| SCHEMBL1051985 | 0.82 | TSHR (0.48) | ALDH1A1SMN1; SMN2OPRM1LMNATSHR | |
| SCHEMBL1685177 | 0.82 | SPHK1 (0.40) | ALDH1A1SMN1; SMN2OPRM1LMNATSHR | |
| SCHEMBL25224640 | 0.82 | SPHK1 (0.45) | ALDH1A1SMN1; SMN2OPRM1LMNATSHR | |
| SCHEMBL6948738 | 0.82 | TSHR (0.40) | ALDH1A1TSHR | |
| SCHEMBL811727 | 0.81 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2OPRM1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133232-B2 | Fused pentacyclic polyethers | UNIVERSITY OF NORTH CAROLINA AT WILMINGTON (US) | 2015-09-15 | — | — | US | disclosed |
| US-20140107060-A1 | Fused Pentacyclic Polyethers | UNIVERSITY OF NORTH CAROLINA AT WILMINGTON (US) | 2014-04-17 | — | — | US | disclosed |
| US-8632792-B2 | Cooling sensation agent composition and sensory stimulation agent composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20130131169-A1 | COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-05-23 | — | — | US | disclosed |
| US-8377458-B2 | Cooling sensation agent composition, sensory stimulation agent composition and use of the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-02-19 | — | — | US | disclosed |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-05-19 | — | — | US | disclosed |
| US-20110081393-A1 | COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME | TAKASAGO INTERNATIONAL CORPORATION | 2011-04-07 | — | — | US | disclosed |
| CN-101185904-B | Selectivity liquid phase hydrogenation catalyst and preparation method and use thereof | UNIV JIANGSU POLYTECHNIC | 2011-01-19 | — | — | CN | disclosed |
| WO-2009123355-A2 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-08 | — | — | WO | disclosed |
| CN-101185904-A | Selectivity liquid phase hydrogenation catalyst and preparation method and use thereof | UNIV JIANGSU POLYTECHNIC (CN) | 2008-05-28 | — | — | CN | disclosed |
| EP-0942943-B1 | METHOD OF PREPARING SMALL PARTICLE DISPERSIONS | KIMBERLY CLARK CO (US) | 2007-04-04 | — | — | EP | disclosed |
| US-6743525-B2 | ELECTROLUMINESCENT DEVICE | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2004-06-01 | — | — | US | disclosed |
| EP-0942943-A1 | METHOD OF PREPARING SMALL PARTICLE DISPERSIONS | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5800866-A | MIXING SURFACTANT, PARTICLES AND NONAQUEOUS SOLVENT | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1998-09-01 | — | — | US | disclosed |
| WO-1998024833-A1 | METHOD OF PREPARING SMALL PARTICLE DISPERSIONS | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1998-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107060-A1 | Fused Pentacyclic Polyethers | MUC1, CFTR, CYSLTR1 | ALDH1A1 129/4885SMN1; SMN2 4232/4885OPRM1 167/4885 |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TRPA1, HRH1, HRH2 | ALDH1A1 520/4885SMN1; SMN2 2144/4885OPRM1 69/4885 |
| US-20110081393-A1 | COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME | TRPA1, TRPV1, TRPM4 | ALDH1A1 685/4885SMN1; SMN2 2797/4885OPRM1 493/4885 |
| US-20130131169-A1 | COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME | TRPA1, TRPV1, TRPM4 | ALDH1A1 685/4885SMN1; SMN2 2797/4885OPRM1 493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.