Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1658716 | 0.92 | ALDH1A1 (0.45) | OPRM1LMNASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL811727 | 0.90 | SMN1; SMN2 (0.55) | OPRM1LMNASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL10416799 | 0.87 | LMNA (0.57) | OPRM1LMNASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL13858888 | 0.86 | OPRM1 (0.58) | OPRM1LMNATP53TSHRCA1 | |
| SCHEMBL1022237 | 0.84 | LMNA (0.54) | OPRM1LMNASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL6003917 | 0.83 | SMN1; SMN2 (0.38) | OPRM1LMNASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL30018032 | 0.83 | SPHK1 (0.48) | OPRM1LMNASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL13817351 | 0.83 | SPHK1 (0.48) | OPRM1LMNASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL13858988 | 0.83 | OPRM1 (0.55) | OPRM1LMNATSHRSPHK1FDPS | |
| SCHEMBL11480610 | 0.83 | OPRM1 (0.55) | OPRM1LMNATSHRSPHK1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8632792-B2 | Cooling sensation agent composition and sensory stimulation agent composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20130131169-A1 | COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-05-23 | — | — | US | disclosed |
| EP-2589058-A1 | PHOTOELECTRIC CONVERSION DEVICE COMPRISING HYDROXAMIC ACID DERIVATIVE OR SALT THEREOF AS ADDITIVE AND PROCESS FOR PRODUCING SAME | BASF SE (DE) | 2013-05-08 | — | — | EP | disclosed |
| US-8377458-B2 | Cooling sensation agent composition, sensory stimulation agent composition and use of the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-02-19 | — | — | US | disclosed |
| US-20120122810-A1 | Fused Pentacyclic Polyethers | UNIVERSITY OF NORTH CAROLINA AT WILMINGTON | 2012-05-17 | — | — | US | disclosed |
| WO-2012001628-A1 | PHOTOELECTRIC CONVERSION DEVICE COMPRISING HYDROXAMIC ACID DERIVATIVE OR SALT THEREOF AS ADDITIVE AND PROCESS FOR PRODUCING SAME | BASF SE (DE) | 2012-01-05 | — | — | WO | disclosed |
| US-20120000533-A1 | PHOTOELECTRIC CONVERSION DEVICE COMPRISING HYDROXAMIC ACID OR A SALT THEREOF AS ADDITIVE AND PROCESS FOR PRODUCING SAME | BASF SE (DE) | 2012-01-05 | — | — | US | disclosed |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-05-19 | — | — | US | disclosed |
| US-20110081393-A1 | COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME | TAKASAGO INTERNATIONAL CORPORATION | 2011-04-07 | — | — | US | disclosed |
| US-20100099643-A1 | Fused Pentacyclic Polyethers | UNIVERSITY OF NORTH CAROLINA AT WILMINGTON | 2010-04-22 | — | — | US | disclosed |
| US-7638500-B2 | Fused pentacyclic polyethers | UNIVERSITY OF NORTH CAROLINA AT WILMINGTON (US) | 2009-12-29 | — | — | US | disclosed |
| WO-2009123355-A2 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-08 | — | — | WO | disclosed |
| US-20070179116-A1 | Fused Pentacyclic Polyethers | UNIVERSITY OF NORTH CAROLINA AT WILMINGTON | 2007-08-02 | — | — | US | disclosed |
| US-7202271-B2 | Fused pentacyclic polyethers | UNIVERSITY OF NORTH CAROLINA (US) | 2007-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179116-A1 | Fused Pentacyclic Polyethers | MUC1, CFTR, CYSLTR1 | OPRM1 167/4885LMNA 4493/4885SMN1; SMN2 4232/4885 |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TRPA1, HRH1, HRH2 | OPRM1 69/4885LMNA 1708/4885SMN1; SMN2 2144/4885 |
| US-20100099643-A1 | Fused Pentacyclic Polyethers | MUC1, CFTR, CYSLTR1 | OPRM1 167/4885LMNA 4493/4885SMN1; SMN2 4232/4885 |
| US-20110081393-A1 | COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME | TRPA1, TRPV1, TRPM4 | OPRM1 493/4885LMNA 1727/4885SMN1; SMN2 2797/4885 |
| US-20130131169-A1 | COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME | TRPA1, TRPV1, TRPM4 | OPRM1 493/4885LMNA 1727/4885SMN1; SMN2 2797/4885 |
| US-20120122810-A1 | Fused Pentacyclic Polyethers | MUC1, CFTR, CYSLTR1 | OPRM1 167/4885LMNA 4493/4885SMN1; SMN2 4232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.