SCHEMBL1658859

SCHEMBL1658859

CC(C)CCCC(C)C(C)O

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.48
BLM P54132 1/20 0.39
CA1 P00915 2/20 0.36
PTPN1 P18031 1/20 0.34
MEN1 O00255 1/20 0.34
CYP3A4 P08684 1/20 0.34
ALOX15 P16050 1/20 0.34
KMT2A Q03164 1/20 0.34
TRPV1 Q8NER1 1/20 0.31
TRPA1 O75762 1/20 0.31
EBP Q15125 1/20 0.30
TSHR P16473 1/20 0.30
CDC25A P30304 1/20 0.30
CDC25B P30305 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1658320 0.94 LMNA (0.48) LMNABLMCA1PTPN1MEN1
SCHEMBL20530409 0.92 LMNA (0.62) LMNABLMCA1PTPN1MEN1
SCHEMBL2555075 0.92 LMNA (0.62) LMNABLMCA1PTPN1MEN1
SCHEMBL2696106 0.82 LMNA (0.48) LMNABLMCA1PTPN1MEN1
SCHEMBL15722824 0.82 TSHR (0.35) TRPV1TRPA1TSHR
SCHEMBL1657177 0.81 CA1 (0.39) LMNACA1TSHR
SCHEMBL15160302 0.78 LMNA (0.43) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL28474503 0.78 LMNA (0.50) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL42290 0.77
SCHEMBL16469538 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6844302-B1 Encapsulated flavor and fragrance INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2005-01-18 US claimed
US-20240410055-A1 METHOD AND FORMULATION FOR PREPARING OPTICAL METAL OXIDE LAYERS MERCK PATENT GMBH (DE) 2024-12-12 US disclosed
CN-118076767-A Method and formulation for producing an optical metal oxide layer 默克专利有限公司 2024-05-24 CN disclosed
WO-2023057401-A1 METHOD AND FORMULATION FOR PREPARING OPTICAL METAL OXIDE LAYERS MERCK PATENT GMBH (DE) 2023-04-13 WO disclosed
CN-105308162-B Compounds for the controlled release of active molecules 弗门尼舍有限公司 2022-10-11 CN disclosed
EP-3180311-B1 METHOD FOR PRODUCING ASTAXANTHIN FROM ASTACIN BASF SE (DE) 2019-04-17 EP disclosed
US-10017464-B2 Process for preparing cyclic alpha-keto alcohols from cyclic alpha-keto enols BASF SE (DE) 2018-07-10 US disclosed
US-10017465-B2 Method for producing astaxanthin from astacin BASF SE (DE) 2018-07-10 US disclosed
US-20170233338-A1 METHOD FOR PRODUCING ASTAXANTHIN FROM ASTACIN BASF SE (DE) 2017-08-17 US disclosed
US-20170217884-A1 PROCESS FOR PREPARING CYCLIC ALPHA-KETO ALCOHOLS FROM CYCLIC ALPHA-KETO ENOLS BASF SE (DE) 2017-08-03 US disclosed
US-8632792-B2 Cooling sensation agent composition and sensory stimulation agent composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-01-21 US disclosed
US-20130157857-A1 INHIBITOR FOR TOBACCO AXILLARY BUD GROWTH AND METHOD FOR INHIBITING TOBACCO AXILLARY BUD GROWTH SDS BIOTECH K.K. (JP) 2013-06-20 US disclosed
US-20130131169-A1 COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-05-23 US disclosed
CN-103096709-A Inhibitor for tobacco axillary bud growth and method for inhibiting tobacco axillary bud growth SDS BIOTECH CORP 2013-05-08 CN disclosed
US-8377458-B2 Cooling sensation agent composition, sensory stimulation agent composition and use of the same TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-02-19 US disclosed
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-05-19 US disclosed
US-20110081393-A1 COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME TAKASAGO INTERNATIONAL CORPORATION 2011-04-07 US disclosed
WO-2009123355-A2 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-10-08 WO disclosed
US-5554588-A IN WHICH AT LEAST HALF COMPRISES ETHERS, AROMATIC METHYL KETONES, ALCOHOLS, ESTERS AND SALICYLATES; DEODORANTS AND ACCEPTABLE FRAGRANCE LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1996-09-10 US disclosed
US-4021461-A INSECTICIDES ZOECON CORPORATION (US) 1977-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170233338-A1 METHOD FOR PRODUCING ASTAXANTHIN FROM ASTACIN ADH1B, ADH5, ADH7 LMNA 2917/4885BLM 1141/4885CA1 987/4885
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TRPA1, HRH1, HRH2 LMNA 1708/4885BLM 4418/4885CA1 3505/4885
US-10017465-B2 Method for producing astaxanthin from astacin ADH1B, ADH5, ADH7 LMNA 2917/4885BLM 1141/4885CA1 987/4885
US-20170217884-A1 PROCESS FOR PREPARING CYCLIC ALPHA-KETO ALCOHOLS FROM CYCLIC ALPHA-KETO ENOLS AKR1C3, AKR1C2, AKR1A1 LMNA 1180/4885BLM 2489/4885CA1 1211/4885
US-10017464-B2 Process for preparing cyclic alpha-keto alcohols from cyclic alpha-keto enols AKR1C3, AKR1C2, AKR1A1 LMNA 1180/4885BLM 2489/4885CA1 1211/4885
US-20110081393-A1 COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME TRPA1, TRPV1, TRPM4 LMNA 1727/4885BLM 4563/4885CA1 1310/4885
US-20130131169-A1 COOLING SENSATION AGENT COMPOSITION, SENSORY STIMULATION AGENT COMPOSITION AND USE OF THE SAME TRPA1, TRPV1, TRPM4 LMNA 1727/4885BLM 4563/4885CA1 1310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.