Sugi Predict

Sugi Predict / Compounds / SCHEMBL165968

SCHEMBL165968

SCHEMBL165968

CC(=N/c1ccccc1C)/C(C)=N\c1ccccc1C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SIGMAR1 Q99720 9/20 0.57
▸ ESR2 Q92731 2/20 0.53
▸ ESR1 P03372 1/20 0.53
▸ GRIN2D O15399 4/20 0.50
▸ GRIN3B O60391 4/20 0.50
▸ GRIN1 Q05586 4/20 0.50
▸ GRIN2A Q12879 4/20 0.50
▸ GRIN2B Q13224 4/20 0.50
▸ GRIN2C Q14957 4/20 0.50
▸ GRIN3A Q8TCU5 4/20 0.50
▸ TSHR P16473 3/20 0.50
▸ KMT2A Q03164 2/20 0.50
▸ MEN1 O00255 1/20 0.50
▸ PABPC1 P11940 1/20 0.50
▸ ALOX15 P16050 1/20 0.50
▸ EBP Q15125 1/20 0.50
▸ TMEM97 Q5BJF2 1/20 0.50
▸ CYP2C9 P11712 1/20 0.47
▸ ACHE P22303 1/20 0.43
▸ ALDH1A1 P00352 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL165969 1.00 SIGMAR1 (0.57) SIGMAR1ESR2ESR1GRIN2DGRIN3B
SCHEMBL29472024 1.00 SIGMAR1 (0.57) SIGMAR1ESR2ESR1GRIN2DGRIN3B
SCHEMBL14816922 1.00 SIGMAR1 (0.57) SIGMAR1ESR2ESR1GRIN2DGRIN3B
SCHEMBL7048441 0.93 SIGMAR1 (0.52) SIGMAR1ESR2ESR1GRIN2DGRIN3B
SCHEMBL6458815 0.93 SIGMAR1 (0.52) SIGMAR1ESR2ESR1GRIN2DGRIN3B
SCHEMBL13727827 0.91 SIGMAR1 (0.50) SIGMAR1ESR2ESR1GRIN2DGRIN3B
SCHEMBL13725213 0.91 SIGMAR1 (0.50) SIGMAR1ESR2ESR1GRIN2DGRIN3B
SCHEMBL5703535 0.91 SIGMAR1 (0.50) SIGMAR1ESR2ESR1GRIN2DGRIN3B
SCHEMBL13727830 0.91 SIGMAR1 (0.50) SIGMAR1ESR2ESR1GRIN2DGRIN3B
SCHEMBL13725211 0.91 SIGMAR1 (0.50) SIGMAR1ESR2ESR1GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1363923-B1 RHODIUM AND IRIDIUM COMPLEXES MERCK PATENT GMBH (DE) 2009-04-01 — — EP claimed
US-7125998-B2 Rhodium and iridium complexes MERCK PATENT GMBH (DE) 2006-10-24 — — US claimed
EP-1562964-B1 PALLADIUM AND PLATINUM COMPLEXES MERCK PATENT GMBH (DE) 2006-07-19 — — EP claimed
EP-1562964-A1 PALLADIUM AND PLATINUM COMPLEXES Covion Organic Semiconductors GmbH (DE) 2005-08-17 — — EP claimed
US-20040138455-A1 Rhodium and iridium complexes MERCK PATENT GMBH (DE) 2004-07-15 — — US claimed
WO-2004041835-A1 PALLADIUM AND PLATINUM COMPLEXES COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2004-05-21 — — WO claimed
EP-1363923-A1 RHODIUM AND IRIDIUM COMPLEXES Covion Organic Semiconductors GmbH (DE) 2003-11-26 — — EP claimed
WO-2002068435-A1 RHODIUM AND IRIDIUM COMPLEXES COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2002-09-06 — — WO claimed
US-12635401-B2 Metal complexes UDC Ireland (IE) 2026-05-19 — — US disclosed
EP-4069709-B1 METAL COMPLEXES UDC IRELAND LTD (IE) 2025-04-23 — — EP disclosed
US-12250871-B2 Metal complexes UDC IRELAND LIMITED (IE) 2025-03-11 — — US disclosed
US-20240260448-A1 Metal Complexes UDC IRELAND LIMITED (IE) 2024-08-01 — — US disclosed
US-11917901-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 — — US disclosed
US-20230056324-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-02-23 — — US disclosed
WO-2004041835-A1 PALLADIUM AND PLATINUM COMPLEXES COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2004-05-21 — — WO disclosed
WO-2004037836-A1 RHODIUM AND IRIDIUM COMPLEXES COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2004-05-06 — — WO disclosed
EP-1363923-A1 RHODIUM AND IRIDIUM COMPLEXES Covion Organic Semiconductors GmbH (DE) 2003-11-26 — — EP disclosed
WO-2002068435-A1 RHODIUM AND IRIDIUM COMPLEXES COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2002-09-06 — — WO disclosed
US-6444831-B2 A MONOOLEFINIC COMPOUND IS ADDED TO A FATTY SUBSTANCE THAT COMPRISES TWO CONJUGATED OR UNCONJUGATED ETHYELNE BONDS IN PRESENCE OF A CATALYTIC SYSTEM CONTAINING IRON COMPOUNDS, A REDUCING AGENT, A LIGAND WHICH CONTAINS NITROGEN, ARSANIC ETC INSTITUT FRANCAIS DU PETROLE (FR) 2002-09-03 — — US disclosed
US-20010005758-A1 Process for the codimerization of polyunsaturated fatty substances and olefins by iron complexes INSTITUT FRANCAIS DE PETROLE (FR) 2001-06-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12635401-B2 Metal complexes SCO2, SOD1, NR4A1 SIGMAR1 453/4885ESR2 93/4885ESR1 765/4885
US-20040138455-A1 Rhodium and iridium complexes RPIA, MPI, INPP5B SIGMAR1 1527/4885ESR2 862/4885ESR1 1000/4885
US-12250871-B2 Metal complexes AP1M1, SOD1, AP3M1 SIGMAR1 4451/4885ESR2 1449/4885ESR1 718/4885
US-20230056324-A1 METAL COMPLEXES MCU, IMMT, SOD1 SIGMAR1 2698/4885ESR2 1569/4885ESR1 1545/4885
US-11917901-B2 Metal complexes MCOLN2, MCOLN1, AP1M1 SIGMAR1 3138/4885ESR2 1547/4885ESR1 1694/4885
US-20240260448-A1 Metal Complexes SOD1, AP1M1, AP3M1 SIGMAR1 4317/4885ESR2 1182/4885ESR1 503/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.