Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17960610 | 0.84 | LMNA (0.50) | LMNAALDH1A1KMT2ANPSR1CYP1A2 | |
| SCHEMBL16596922 | 0.82 | LMNA (0.48) | LMNAALDH1A1KMT2ANPSR1CYP1A2 | |
| SCHEMBL16586347 | 0.82 | LMNA (0.48) | LMNAALDH1A1KMT2ANPSR1CYP1A2 | |
| SCHEMBL17975237 | 0.81 | CYP1A2 (0.51) | LMNAALDH1A1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL16596946 | 0.79 | LMNA (0.45) | LMNAALDH1A1KMT2ANPSR1CYP1A2 | |
| SCHEMBL16596917 | 0.78 | ALDH1A1 (0.50) | LMNAALDH1A1KMT2ANPSR1CYP1A2 | |
| SCHEMBL3588982 | 0.76 | ALDH1A1 (0.56) | LMNAALDH1A1KMT2ANPSR1CYP1A2 | |
| SCHEMBL16596915 | 0.71 | HTT (0.46) | LMNAALDH1A1KMT2ANPSR1HTT | |
| SCHEMBL17975232 | 0.68 | KMT2A (0.48) | LMNAALDH1A1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL17960722 | 0.68 | MGAM (0.37) | LMNAALDH1A1KMT2ANPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10093692-B2 | Phosphines, synthesis thereof and their use in catalysis | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2018-10-09 | — | — | US | claimed |
| US-20160222042-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2016-08-04 | — | — | US | claimed |
| US-10093692-B2 | Phosphines, synthesis thereof and their use in catalysis | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2018-10-09 | — | — | US | disclosed |
| US-20160222042-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2016-08-04 | — | — | US | disclosed |
| US-20160222042-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2016-08-04 | — | — | US | disclosed |
| WO-2015039606-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2015-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160222042-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | PHOSPHO1, PPIP5K2, PDXK | LMNA 4653/4885ALDH1A1 3824/4885KMT2A 1445/4885 |
| US-10093692-B2 | Phosphines, synthesis thereof and their use in catalysis | PPIP5K2, PHOSPHO1, ITPA | LMNA 4529/4885ALDH1A1 3683/4885KMT2A 1414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.