Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.37 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SI | P14410 | 2/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17960699 | 0.87 | LMNA (0.36) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL16596922 | 0.85 | LMNA (0.48) | LMNAALDH1A1MAPTTSHRKMT2A | |
| SCHEMBL17975242 | 0.83 | MGAM (0.41) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL17960575 | 0.81 | PTGES (0.35) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL17960724 | 0.79 | PTGES (0.36) | GAALMNAALDH1A1MAPTKDM4E | |
| SCHEMBL16596912 | 0.77 | PTGES (0.42) | GAALMNAALDH1A1KDM4EHPGD | |
| SCHEMBL16596945 | 0.76 | PTGES (0.41) | GAALMNAALDH1A1KDM4EHPGD | |
| SCHEMBL16596881 | 0.75 | PTGES (0.37) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL13978408 | 0.74 | ALDH1A1 (0.47) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL17960678 | 0.73 | PTGES (0.33) | ALDH1A1KDM4EHPGDTSHRPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10093692-B2 | Phosphines, synthesis thereof and their use in catalysis | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2018-10-09 | — | — | US | claimed |
| US-20160222042-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2016-08-04 | — | — | US | claimed |
| US-10093692-B2 | Phosphines, synthesis thereof and their use in catalysis | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2018-10-09 | — | — | US | disclosed |
| US-20160222042-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2016-08-04 | — | — | US | disclosed |
| US-20160222042-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160222042-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | PHOSPHO1, PPIP5K2, PDXK | MGAM 812/4885AMY1A 2867/4885GAA 2476/4885 |
| US-10093692-B2 | Phosphines, synthesis thereof and their use in catalysis | PPIP5K2, PHOSPHO1, ITPA | MGAM 754/4885AMY1A 3195/4885GAA 2219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.