Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16596946 | 0.87 | LMNA (0.45) | ALDH1A1SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL17975238 | 0.85 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2TSHRKMT2AMEN1 | |
| SCHEMBL15921010 | 0.73 | LMNA (0.51) | SMN1; SMN2KMT2AMEN1MAPK1LMNA | |
| SCHEMBL16596914 | 0.71 | KMT2A (0.49) | HTTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL16596919 | 0.71 | LMNA (0.52) | HTTALDH1A1SMN1; SMN2TSHRKMT2A | |
| SCHEMBL16596945 | 0.69 | PTGES (0.41) | HTTALDH1A1SMN1; SMN2TSHRLMNA | |
| SCHEMBL13502463 | 0.68 | ALDH1A1 (0.55) | HTTP2RX4ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL16596912 | 0.68 | PTGES (0.42) | HTTALDH1A1SMN1; SMN2TSHRLMNA | |
| SCHEMBL17960610 | 0.67 | LMNA (0.50) | HTTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL17975236 | 0.67 | PTGES (0.39) | HTTALDH1A1SMN1; SMN2TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10093692-B2 | Phosphines, synthesis thereof and their use in catalysis | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2018-10-09 | — | — | US | claimed |
| US-20160222042-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2016-08-04 | — | — | US | claimed |
| US-10093692-B2 | Phosphines, synthesis thereof and their use in catalysis | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2018-10-09 | — | — | US | disclosed |
| US-20160222042-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2016-08-04 | — | — | US | disclosed |
| US-20160222042-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2016-08-04 | — | — | US | disclosed |
| WO-2015039606-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2015-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160222042-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | PHOSPHO1, PPIP5K2, PDXK | HTT 4681/4885P2RX4 965/4885ALDH1A1 3824/4885 |
| US-10093692-B2 | Phosphines, synthesis thereof and their use in catalysis | PPIP5K2, PHOSPHO1, ITPA | HTT 4539/4885P2RX4 1105/4885ALDH1A1 3683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.