Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16596912 | 0.99 | PTGES (0.42) | PTGESSMN1; SMN2LMNAALDH1A1TP53 | |
| SCHEMBL17975236 | 0.86 | PTGES (0.39) | PTGESSMN1; SMN2LMNAALDH1A1TP53 | |
| SCHEMBL17975244 | 0.85 | PTGES (0.39) | PTGESSMN1; SMN2LMNAALDH1A1TP53 | |
| SCHEMBL16596946 | 0.81 | LMNA (0.45) | SMN1; SMN2LMNAALDH1A1TP53TSHR | |
| SCHEMBL17960575 | 0.81 | PTGES (0.35) | PTGESSMN1; SMN2LMNAALDH1A1TP53 | |
| SCHEMBL17960724 | 0.79 | PTGES (0.36) | PTGESSMN1; SMN2LMNAALDH1A1HTT | |
| SCHEMBL17960722 | 0.76 | MGAM (0.37) | PTGESSMN1; SMN2LMNAALDH1A1TSHR | |
| SCHEMBL17960678 | 0.75 | PTGES (0.33) | PTGESSMN1; SMN2ALDH1A1TSHRHPGD | |
| SCHEMBL16596881 | 0.75 | PTGES (0.37) | PTGESSMN1; SMN2LMNAALDH1A1TP53 | |
| SCHEMBL17960699 | 0.75 | LMNA (0.36) | PTGESLMNAALDH1A1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10093692-B2 | Phosphines, synthesis thereof and their use in catalysis | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2018-10-09 | — | — | US | claimed |
| US-20160222042-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2016-08-04 | — | — | US | claimed |
| US-10093692-B2 | Phosphines, synthesis thereof and their use in catalysis | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2018-10-09 | — | — | US | disclosed |
| US-20160222042-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2016-08-04 | — | — | US | disclosed |
| US-20160222042-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2016-08-04 | — | — | US | disclosed |
| WO-2015039606-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2015-03-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160222042-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | PHOSPHO1, PPIP5K2, PDXK | PTGES 2053/4885SMN1; SMN2 4585/4885LMNA 4653/4885 |
| US-10093692-B2 | Phosphines, synthesis thereof and their use in catalysis | PPIP5K2, PHOSPHO1, ITPA | PTGES 1962/4885SMN1; SMN2 4251/4885LMNA 4529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.