Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525950 | 0.80 | KMT2A (0.45) | ALDH1A1HPGDMAPTKMT2ATSHR | |
| SCHEMBL21612064 | 0.78 | KDM4E (0.47) | ALDH1A1HPGDMAPTKMT2ATSHR | |
| SCHEMBL20893703 | 0.78 | KMT2A (0.44) | ALDH1A1HPGDMAPTKMT2ATSHR | |
| SCHEMBL21612131 | 0.78 | KMT2A (0.48) | ALDH1A1HPGDMAPTKMT2ATSHR | |
| SCHEMBL2809243 | 0.78 | MAPT (0.56) | ALDH1A1HPGDMAPTKMT2ATSHR | |
| SCHEMBL23531571 | 0.78 | ALDH1A1 (0.48) | ALDH1A1HPGDMAPTKMT2ATSHR | |
| SCHEMBL20894354 | 0.77 | MAPT (0.42) | ALDH1A1HPGDMAPTKMT2ATSHR | |
| SCHEMBL21612056 | 0.77 | ALDH1A1 (0.45) | ALDH1A1HPGDTSHRKDM4ERAB9A | |
| SCHEMBL23531547 | 0.76 | MAPT (0.41) | ALDH1A1HPGDMAPTKMT2ATSHR | |
| SCHEMBL2951166 | 0.74 | ALDH1A1 (0.45) | ALDH1A1HPGDMAPTKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11884643-B2 | Substituted thiophenecarboxamides and analogues as antibacterials agents | BAYER AKTIENGESELLSCHAFT (DE) | 2024-01-30 | — | — | US | claimed |
| EP-3818050-B1 | SUBSTITUTED THIOPHENECARBOXAMIDES AND ANALOGUES AS ANTIBACTERIALS AGENTS | BAYER AG (DE) | 2023-05-31 | — | — | EP | claimed |
| US-20230159506-A1 | SUBSTITUTED THIOPHENECARBOXAMIDES AND ANALOGUES AS ANTIBACTERIALS AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-05-25 | — | — | US | claimed |
| EP-3818050-A1 | SUBSTITUTED THIOPHENECARBOXAMIDES AND ANALOGUES AS ANTIBACTERIALS AGENTS | Bayer Aktiengesellschaft (DE) | 2021-05-12 | — | — | EP | claimed |
| CN-112638893-A | Substituted thiophenecarboxamides and analogs as antibacterial agents | 拜耳公司 | 2021-04-09 | — | — | CN | claimed |
| WO-2020007905-A1 | SUBSTITUTED THIOPHENECARBOXAMIDES AND ANALOGUES AS ANTIBACTERIALS AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-01-09 | — | — | WO | claimed |
| US-12516037-B2 | Substituted thiophenecarboxamides and analogues as antibacterials agents | BAYER AKTIENGESELLSCHAFT (DE) | 2026-01-06 | — | — | US | disclosed |
| US-20240360098-A1 | SUBSTITUTED THIOPHENECARBOXAMIDES AND ANALOGUES AS ANTIBACTERIALS AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2024-10-31 | — | — | US | disclosed |
| US-11952359-B2 | Substituted thiophenecarboxamides and analogues as antibacterials agents | BAYER AKTIENGESELLSCHAFT (DE) | 2024-04-09 | — | — | US | disclosed |
| CN-112601744-B | Substituted thiophenecarboxamides and analogues as antibacterial agents | 拜耳公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-112638893-B | Substituted thiophenecarboxamides and analogues as antibacterial agents | 拜耳公司 | 2024-03-29 | — | — | CN | disclosed |
| US-11884643-B2 | Substituted thiophenecarboxamides and analogues as antibacterials agents | BAYER AKTIENGESELLSCHAFT (DE) | 2024-01-30 | — | — | US | disclosed |
| EP-3818050-B1 | SUBSTITUTED THIOPHENECARBOXAMIDES AND ANALOGUES AS ANTIBACTERIALS AGENTS | BAYER AG (DE) | 2023-05-31 | — | — | EP | disclosed |
| US-20140235817-A1 | SEMICONDUCTING POLYMERS | UNIVERSITY OF CHICAGO (US) | 2014-08-21 | — | — | US | disclosed |
| US-8653228-B2 | Semiconducting polymers | UNIVERSITY OF CHICAGO (US) | 2014-02-18 | — | — | US | disclosed |
| US-20140005347-A1 | SEMICONDUCTING POLYMERS | UNIVERSITY OF CHICAGO (US) | 2014-01-02 | — | — | US | disclosed |
| US-8436134-B2 | Semiconducting polymers | UNIVERSITY OF CHICAGO (US) | 2013-05-07 | — | — | US | disclosed |
| US-20110124822-A1 | SEMICONDUCTING POLYMERS | NATIONAL SCIENCE FOUNDATION | 2011-05-26 | — | — | US | disclosed |
| EP-2307483-A1 | SEMICONDUCTING POLYMERS | University Of Chicago (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2010008672-A1 | SEMICONDUCTING POLYMERS | UNIVERSITY OF CHICAGO (US) | 2010-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11884643-B2 | Substituted thiophenecarboxamides and analogues as antibacterials agents | XDH, TST, BLVRB | ALDH1A1 4641/4885HPGD 1624/4885MAPT 4393/4885 |
| US-20240360098-A1 | SUBSTITUTED THIOPHENECARBOXAMIDES AND ANALOGUES AS ANTIBACTERIALS AGENTS | TST, TBK1, PGLS | ALDH1A1 4717/4885HPGD 2540/4885MAPT 3896/4885 |
| US-20230159506-A1 | SUBSTITUTED THIOPHENECARBOXAMIDES AND ANALOGUES AS ANTIBACTERIALS AGENTS | XDH, TST, BLVRB | ALDH1A1 4641/4885HPGD 1624/4885MAPT 4393/4885 |
| US-11952359-B2 | Substituted thiophenecarboxamides and analogues as antibacterials agents | TST, XDH, PGLS | ALDH1A1 4288/4885HPGD 1896/4885MAPT 4385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.