Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.42 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1660016 | 0.84 | TDP1 (0.47) | MMP1BAZ2BBAZ2ANPC1RAB9A | |
| SCHEMBL388580 | 0.75 | BAZ2B (0.70) | BAZ2BBAZ2ARAB9AMAPTKDM4E | |
| SCHEMBL1641936 | 0.74 | KDM4E (0.57) | MAPTKDM4EKMT2A | |
| SCHEMBL1658699 | 0.72 | L3MBTL1 (0.53) | MMP12MMP1BAZ2BBAZ2ANPC1 | |
| SCHEMBL1662612 | 0.72 | MEN1 (0.51) | BAZ2BBAZ2ANPC1RAB9AKDM4E | |
| SCHEMBL5943427 | 0.72 | TDP1 (0.61) | MMP12MMP1MAPTTDP1GPBAR1 | |
| SCHEMBL1660685 | 0.71 | TSHR (0.53) | BAZ2BBAZ2AMAPTTDP1KDM4E | |
| SCHEMBL26235469 | 0.70 | BRD4 (0.49) | BAZ2BBAZ2ATDP1KDM4ETSHR | |
| SCHEMBL13885760 | 0.69 | KMT2A (0.74) | MMP12MMP1TDP1KDM4EMAOB | |
| SCHEMBL27703225 | 0.69 | MMP12 (0.51) | MMP12MMP1MAPTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2306828-A1 | PROLYL HYDROXYLASE INHIBITORS | Glaxosmithkline LLC (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009158315-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-30 | — | — | WO | disclosed |