Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.52 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 2/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27600762 | 0.79 | CASP3 (0.69) | L3MBTL1CASP3SENP8SENP7SENP6 | |
| SCHEMBL10894226 | 0.78 | SERPINE1 (0.59) | L3MBTL1CASP3SENP8SENP7SENP6 | |
| SCHEMBL28254056 | 0.77 | CASP3 (0.68) | L3MBTL1CASP3SENP8SENP7SENP6 | |
| SCHEMBL28884251 | 0.77 | L3MBTL1 (0.72) | L3MBTL1CASP3SENP8SENP7SENP6 | |
| SCHEMBL388580 | 0.76 | BAZ2B (0.70) | L3MBTL1BAZ2BBAZ2AALDH1A1MEN1 | |
| SCHEMBL1662612 | 0.75 | MEN1 (0.51) | BAZ2BBAZ2AALDH1A1NPC1MEN1 | |
| SCHEMBL1660016 | 0.75 | TDP1 (0.47) | L3MBTL1BAZ2BBAZ2AALDH1A1HTT | |
| SCHEMBL1642110 | 0.73 | HSP90AA1 (0.48) | ALDH1A1NPC1MEN1KMT2ARAB9A | |
| SCHEMBL1660685 | 0.72 | TSHR (0.53) | L3MBTL1BAZ2BBAZ2AALDH1A1MEN1 | |
| SCHEMBL1659999 | 0.72 | MMP12 (0.46) | BAZ2BBAZ2ANPC1KMT2AMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2306828-A1 | PROLYL HYDROXYLASE INHIBITORS | Glaxosmithkline LLC (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009158315-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-30 | — | — | WO | disclosed |